- STIRIPENTOL
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- $714.30 / 1Kg/Bag
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2021-11-02
- CAS:49763-96-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500kg
- STIRIPENTOL USP/EP/BP
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- $1.10 / 1g
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2021-08-18
- CAS:49763-96-4
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons min
- Stiripentol
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- $15.00 / 1KG
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2021-07-02
- CAS:49763-96-4
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | STIRIPENTOL Basic information |
| Product Name: | STIRIPENTOL | | Synonyms: | (RS)-(E)-4,4-dimethyl-1-[3,4(methylenedioxy)-phenyl]-1-penten-3-ol;1-(1,3-BENZODIOXOL-5YL)-4,4-DIMETHYL-1-PENTEN-3-OL;STIRIPENTOL;1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-o;4,4-dimethyl-1-(3,4-methylenedioxyphenyl)-1-penten-3-o;4,4-dimethyl-1-(3,4-methylenedioxyphenyl)-1-penten-3-ol;bcx2600;1-(Benzo[d][1,3]dioxol-5-yl)-4,4-dimethylpent-1-en-3-ol | | CAS: | 49763-96-4 | | MF: | C14H18O3 | | MW: | 234.29 | | EINECS: | 256-480-9 | | Product Categories: | Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 49763-96-4.mol |  |
| | STIRIPENTOL Chemical Properties |
| Melting point | 73-74°C | | Boiling point | 365.4±11.0 °C(Predicted) | | density | 1.139±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO: ≥20mg/mL | | pka | 14.45±0.20(Predicted) | | form | powder | | color | white to beige | | InChIKey | IBLNKMRFIPWSOY-FNORWQNLSA-N | | CAS DataBase Reference | 49763-96-4 |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 | | RTECS | SB3393000 | | HS Code | 2932.99.7000 |
| | STIRIPENTOL Usage And Synthesis |
| Description | Stiripentol is a third-generation antiepileptic compound. It is a positive allosteric modulator of GABAA receptors, potentiating GABA-mediated activation to a greater extent in receptors expressing α3 subunits and to a lower extent in those containing β1 or ε subunits. It also inhibits GABA reuptake in vitro and increases the release of GABA in neonatal rat hippocampal slices. Stiripentol (500 μM) inhibits lactate dehydrogenase (LDH), blocking both lactate-to-pyruvate and pyruvate-to-lactate conversions by human LDH1 and LDH5. Formulations containing stiripentol have been used in the adjunctive treatment of seizures associated with Dravet syndrome. | | Chemical Properties | White Solid | | Uses | Stiripentol has been used in pharmacokinetic analysis and as a reference standard in fluorescence spectra analysis. | | Uses | An antiepileptic drug | | Uses | Stiripentol is an epilepsy drug, it has been used as co-therapy for treatment of epilepsy. | | Definition | ChEBI: 1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol is a phenylpropanoid. | | Biochem/physiol Actions | Anti-convulsant drug |
| | STIRIPENTOL Preparation Products And Raw materials |
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