- HA14-1
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- $2.00 / 1kg
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2019-07-06
- CAS:65673-63-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
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| Product Name: | HA14-1 | | Synonyms: | 2-Amino-6-bromo-alpha-cyano-3-(ethoxycarbonyl)-(4H)-1-benzopyrane-4-aceticacidethylester;ethyl 6-broMo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chroMene-3-carboxylate;2-Amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester, Ethyl [2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)]-4H-chromene-3-carboxylate;[Ethyl 2-amino-6-bromo-4-(1cyano-2-ethoxy-2-oxoethyl)-4H-chromene3-3carboxylate], Ethyl [2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)]-4H-chromene-3-carboxylate;2-Amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-aceticacidethylester;2-Amino-6-bromo-alpha-cyano-3-(ethoxycarbonyl)-(alphaR,4R)-rel-4H-1-benzopyran-4-acetic acid ethyl ester;Ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-1-benzopyran-3-carboxylate 97%;HA 14-1, Ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate, 2-[2-Amino-6-bromo-3-(ethoxycarbonyl)-4H-chromen-4-yl]-3-ethoxy-3-oxopropanenitrile | | CAS: | 65673-63-4 | | MF: | C17H17BrN2O5 | | MW: | 409.23 | | EINECS: | | | Product Categories: | Inhibitors;Caspases/Apoptosis;Inhibitor | | Mol File: | 65673-63-4.mol |  |
| | HA14-1 Chemical Properties |
| Melting point | 105 °C | | density | 1.480 | | storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C | | solubility | DMSO: 26 mg/mL | | form | powder | | CAS DataBase Reference | 65673-63-4 |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | HS Code | 29322090 |
| | HA14-1 Usage And Synthesis |
| Uses | HA14-1 is a cell-permeable, nonpeptidic Bcl-2 inhibitor. | | Definition | ChEBI: 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-1-benzopyran-3-carboxylic acid ethyl ester is a 1-benzopyran. | | Biological Activity | Cell-permeable inhibitor of Bcl-2 protein (IC 50 ~ 9 μ M); acts by binding to the surface pocket. Disrupts Bax/Bcl-2 interaction and induces apoptosis of tumor cells. | | Biochem/physiol Actions | HA 14-1 is a nonpeptide apoptosis inducer; Bcl-2 antagonist. |
| | HA14-1 Preparation Products And Raw materials |
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