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| | (1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide Basic information |
| Product Name: | (1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide | | Synonyms: | (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide;(1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide;Cyclopropanecarboxamide, 2-(3,4-difluorophenyl)-, (1R,2R)-;(1R,2R)-2-(3,4-difluorophenyl)-1-cyclopropanecarboxamide;Ticagrelor (1R,2R)-Carboxamide;(1R, 2R) -2- (3, 4-difluorophenyl) Carboxamide;(1R, 2S) -2- (3,4-difluorophenyl) cyclopropamide;(1R, 2R) -2- (3,4-difluorophenyl) cyclopropane formamide | | CAS: | 1006376-62-0 | | MF: | C10H9F2NO | | MW: | 197.18 | | EINECS: | 600-115-1 | | Product Categories: | | | Mol File: | 1006376-62-0.mol |  |
| | (1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide Chemical Properties |
| Melting point | 145 - 147°C | | Boiling point | 347.9±42.0 °C(Predicted) | | density | 1.366±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 16.43±0.40(Predicted) | | color | White to Off-White |
| | (1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide Usage And Synthesis |
| Uses | (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxamide is a part of the synthetic preparation of the synthesis and inhibitory effect on ADP-induced platelet aggregation of ticagrelor derivatives as antiplatelets agents. |
| | (1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide Preparation Products And Raw materials |
| Raw materials | Cyclopropanecarbonyl chloride, 2-(3,4-difluorophenyl)-, (1R,2R)--->2-Chloro-1-(3,4-difluoro-phenyl)-ethanone-->(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarbonitrile-->(1R,2R)-ethyl2-(3,4-difluorophenyl)cyclopropane carboxylate-->(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol-->(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid-->1,2-Difluorobenzene |
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