TLR4-IN-C34
| 中文名称 | TLR4-IN-C34 |
|---|---|
| 中文同义词 | ISOPROPYL 2-(ACETYLAMINO)-2-DEOXY á-D-GLUCOPYRANOSIDE 3,4,6-TRIACETATE;(2R,3S,4R,5R,6S)-5-乙酰氨基-2-(乙酰氧基甲基)-6-异丙氧基四氢-2H-吡喃-3,4-二基 二乙酸酯;化合物TLR4-IN-C34;异丙基2-乙酰氨基-3,4,6-三-O-乙酰基-2-脱氧-Α-D-吡喃葡萄糖苷;猴子补体蛋白4(C4)ELISA试剂盒;C34,TLR4抑制剂 |
| 英文名称 | Isopropyl 2-(acetylamino)-2-deoxy á-D-glucopyranoside 3,4,6-triacetate |
| 英文同义词 | 2-Acetamidopyranoside;C34;Isopropyl 2-(acetylamino)-2-deoxy á-D-glucopyranoside 3,4,6-triacetate;TLR4-IN-C34;TLR4-C34;(2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4-diyl diacetate;ISOPROPYL 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSIDE 3,4,6-TRIACETATE;Isopropyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranoside |
| CAS号 | 40592-88-9 |
| 分子式 | C17H27NO9 |
| 分子量 | 389.39758 |
| EINECS号 | |
| 相关类别 | 抑制剂;试剂盒-Elisa试剂盒;API |
| Mol文件 | 40592-88-9.mol |
| 结构式 |  |
TLR4-IN-C34 性质
| 沸点 | 519.8±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.21±0.1 g/cm3(Predicted) |
| 储存条件 | -20°C |
| 溶解度 | H2O: 可溶1mg/mL, 澄清 (加热) |
| 形态 | 粉末 |
| 酸度系数(pKa) | 13?+-.0.70(Predicted) |
| 颜色 | 白色至米色 |
TLR4-IN-C34是一类新的toll样受体4 (TLR4)抑制剂，是潜在的抗炎药物。TLR4-IN-C34 是具有口服活性的 TLR4 抑制剂，可改善内毒素血症和坏死性小肠结肠炎模型的全身炎症。
TLR4-IN-C34 (C34, 1 mg/kg, orally daily) could attenuate NEC severity and demonstrates a marked preservation of the intestinal mucosa.
| Animal Model: | Experimental NEC induced in 7-8 day old mice. |
| Dosage: | 1 mg/kg. |
| Administration: | Orally every morning. |
| Result: | Attenuated intestinal inflammation. |
安全信息
| WGK Germany | 3 |
|---|---|
| 海关编码 | 2938900000 |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-107575 | TLR4-IN-C34 | 1 mg | 280元 | |
| 2024/04/30 | HY-107575 | TLR4-IN-C34 TLR4-IN-C34 | 40592-88-9 | 5mg | 700元 |