2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇

2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇

中文名称2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇
中文同义词2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇
英文名称2-(3,4-Dihydroxyphenyl)-2-((2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl)oxy)chroman-3,4,5,7-tetraol
英文同义词-2-((2-(3,4-dihydroxyphenyl);-5,7-dihydroxychroman-3-yl);chroman-3,4,5,7-tetraol;Proanthocyanidins(b);2H-1-Benzopyran-3,4,5,7-tetrol, 2-(3,4-dihydroxyphenyl)-2-[[2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl]oxy]-3,4-dihydro-;inhibit,Proanthocyanidins,Fungal,Bacterial,Inhibitor;Catechin Impurity 14
CAS号20347-71-1
分子式C30H26O13
分子量594.52
EINECS号
相关类别标准品
Mol文件20347-71-1.mol
结构式2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇 结构式

2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇 性质

沸点986.4±65.0 °C(Predicted)
密度1.87±0.1 g/cm3(Predicted)
储存条件under inert gas (nitrogen or Argon) at 2-8°C
溶解度DMF:3mg/mL; DMSO:10mg/mL;乙醇:0.5mg/mL; PBS(pH 7.2):10 mg/mL
形态固体
酸度系数(pKa)9.24±0.70(Predicted)

2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇 用途与合成方法

Proanthocyanidins 是一类在高等植物中广泛分布的多酚化合物,由亲电子黄烷酰基单元组成。Proanthocyanidins 可用作抗氧化剂和抗癌剂。Proanthocyanidins 还显示出抗炎,保护心脏,抗菌和抗真菌的特性,可用于研究慢性静脉功能不全、毛细血管脆弱、晒伤和视网膜病变。

Proanthocyanidins are present in plants as complex mixtures of polymers. Predominant food sources are red wine, tea, chocolate and fruits like grapes, apples, pears, and cranberries.
The most interesting antibacterial activity of Proanthocyanidins is related to their presence in cranberries ( Vaccinium macrocarpon Ait.). A number of clinical trials have demonstrated the effectiveness of cranberry consumption in preventing urinary tract infections (UTIs). Although UTIs can be caused by many microorganisms, more than 85% are caused by Escherichia coli. The presence of P-fimbriae on E. coli , which are proteinaceous fibers on the bacterial cell wall, has been clearly established as a virulence factor, since they are responsible by producing adhesions for adherence to uroepithelial cells. Recently, it is demonstrated that cranberry Proanthocyanidins might inhibit P-fimbriated E. coli from adhering to uroepithelial cells. The antiadhesion activity of cranberry juice appears to be related to the presence of Proanthocyanidins with at least one A-type linkage.

The effects of cacao liquor Proanthocyanidins on 2- amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced mutagenesis in vivo carcinogenesis in female Sprague-Dawley rats are investigated. In the Ames assay, Proanthocyanidins shows strong antimutagenic effects when assayed in the presence of S-9 mixture. They also inhibit significantly rat pancreatic carcinogenesis in the initiation stage, but not mammary carcinogenesis.

安全信息

MSDS信息

更新日期产品编号产品名称CAS号包装价格
2024/01/16S51052-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇
Proanthocyanidins
20347-71-125mg795.42元
2024/01/16S5105Proanthocyanidins20347-71-11g7944.3元

2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇 上下游产品信息

"2-(3,4-二羟基苯基)-2-((2-(3,4-二羟基苯基)-5,7-二氢色满-3-基)氧基)苯并二氢吡喃-3,4,5,7-四醇"相关产品信息
原花青素B2-3,3'-二-O-没食子酸酯 原花青素A1 原花青素B2-3''-O-没食子酸酯 原花青素A2 原人参三醇 月桂(LAURUSNOBILIS)叶提取物 尿嘧啶 二乙醇胺 二羟基苯甲酸 间苯二酚 3-(3,5-二叔丁基-4-羟基苯基)丙酸 二氢咖啡酸 二苯基氧膦 原花青素C1 原薯蓣皂甙 原花青素B1 原花青素B2
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