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| | Apixaban Dehydro Impurity Basic information |
| Product Name: | Apixaban Dehydro Impurity | | Synonyms: | Apixaban Dehydro Impurity;4,5-Dehydro Apixaban;Apixaban 4,5-Dehydro Impurity;Apixaban Impurity TQ;Apixaban 4,5-Dehydro Imp;Apixaban impurity 11/4,5-Dehydro Apixaban/Apixaban dehydro Impurity/1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide;Dehydro Apixaban;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | | CAS: | 1074549-89-5 | | MF: | C25H23N5O4 | | MW: | 457.48 | | EINECS: | 604-604-1 | | Product Categories: | | | Mol File: | 1074549-89-5.mol |  |
| | Apixaban Dehydro Impurity Chemical Properties |
| Melting point | >252°C (dec.) | | Boiling point | 770.0±60.0 °C(Predicted) | | density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | pka | 14.67±0.20(Predicted) | | form | Solid | | color | White to Pale Beige |
| | Apixaban Dehydro Impurity Usage And Synthesis |
| Uses | 4,5-Dehydro Apixaban is an impurity of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation |
| | Apixaban Dehydro Impurity Preparation Products And Raw materials |
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