普兰林肽
| 中文名称 | 普兰林肽 |
|---|---|
| 中文同义词 | 普兰林肽(规格,价格请询问客服) |
| 英文名称 | Pramlintide |
| 英文同义词 | Triproamylin;Lys-c[Cys-Asn-Thr-Ala-Thr-Cys]-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu -Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly -Ser-Asn-Thr-Tyr-NH2;CL062;Pramlintide D10;PramlintideQ: What is Pramlintide Q: What is the CAS Number of Pramlintide Q: What is the storage condition of Pramlintide Q: What are the applications of Pramlintide;Pramlintide |
| CAS号 | 151126-32-8 |
| 分子式 | C171H267N51O53S2.C2H4O2.H2O |
| 分子量 | 4027.49 |
| EINECS号 | 1592732-453-0 |
| 相关类别 | 药物多肽 |
| Mol文件 | 151126-32-8.mol |
| 结构式 |  |
普兰林肽 性质
| 溶解度 | 溶于水 |
|---|---|
| 形态 | 固体 |
| 颜色 | 白色 |
| 水溶解性 | Soluble to 1 mg/ml in water |
Pramlintide 是一种人胰淀粉样多肽类似物。Pramlintide 是一种抗糖尿病剂，也可用于肠癌的研究。
Pramlintide inhibits the growth of HCT-116 and HT-29 in a dose-dependent manner, with higher efficacy against the latter (IC
50
s of 48.67 and 9.10 μg/mL, respectively).
The addition of 5, 10, and 20 μg/mL of Pramlintide to HCT-116 and HT-29 with 5-fluorouracil, Oxaliplatin, or Irinotecan induces the antiproliferative effect synergistically.