| Company Name: |
Clearsynth Labs Limited
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| Tel: |
+91-22-26355700 |
| Email: |
info@clearsynth.com |
| Products Intro: |
Product Name:trans/cis Resveratrol-D4
CAS:1089051-56-8
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:trans-Resveratrol-d4
CAS:1089051-56-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Hubei Xinyang Medical Technology Co., Ltd
|
| Tel: |
15347293736 15347293736 |
| Email: |
2853117764@qq.com |
| Products Intro: |
Product Name:Resveratrol-d4
CAS:1089051-56-8
Purity:99% HPLC Package:10mg；25mg；50mg；100mg
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| | trans/cis Resveratrol-D4 Basic information |
| Product Name: | trans/cis Resveratrol-D4 | | Synonyms: | trans/cis Resveratrol-D4;Resveratrol D4Q: What is
Resveratrol D4 Q: What is the CAS Number of
Resveratrol D4 Q: What is the storage condition of
Resveratrol D4 Q: What are the applications of
Resveratrol D4;5-[(E)-2-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)ethenyl]benzene-1,3-diol | | CAS: | 1089051-56-8 | | MF: | C14H8D4O3 | | MW: | 232.267927112 | | EINECS: | | | Product Categories: | | | Mol File: | 1089051-56-8.mol |  |
| | trans/cis Resveratrol-D4 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: >100 mg/ml,DMSO: >50mg/ml,Ethanol: >50mg/ml,PBS (pH 7.2): <100 μg/ml |
| | trans/cis Resveratrol-D4 Usage And Synthesis |
| Description | trans-Resveratrol-d4 is intended for use as an internal standard for the quantification of trans-resveratrol by GC- or LC-MS. trans-Resveratrol is a polyphenolic phytoalexin found in a variety of plants, including grapes, that has anti-inflammatory, antioxidant, and anticancer activities. It inhibits the cyclooxygenase and hydroperoxidase activities of COX-1 (EC50s = 15 and 3.7 μM, respectively), but not COX-2 (EC50s = >100 μM and 85 μM, respectively). trans-Resveratrol (3 and 8 mg/kg) inhibits carrageenan-induced paw edema in mice. It inhibits free radical formation in HL-60 human promyelocytic leukemia cells induced by phorbol 12-myristate 13-acetate (TPA; ; EC50 = 27 μM). trans-Resveratrol (1-25 μmol) reduces both the incidence and number of tumors in a two-stage mouse model of skin cancer induced by TPA and 7,12-dimethyl-benz[a]anthracene (DMBA). trans-Resveratrol (200 μM) also activates sirtuin 1 (SIRT1) by 8-fold in vitro and inhibits a variety of targets including ERK1, JNK1, Src, PKCα, aromatase/CYP19, and DNA polymerases α and δ (IC50s = 37, 50, 20, <10, 25, 3.3, and 5 μM, respectively) in vitro and/or ex vivo. It prolongs lifespan in model organisms including C. elegans, D. melanogaster, and mice. | | Uses | Resveratrol-d4 is labelled Resveratrol (R150000) which is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. |
| | trans/cis Resveratrol-D4 Preparation Products And Raw materials |
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