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Timolol

Timolol Suppliers list
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Email: sales@mainchem.com
Products Intro: Product Name:Timolol
CAS:26839-75-8
Company Name: Chemwill Asia Co.,Ltd.
Tel: 86-21-51086038
Email: chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com
Products Intro: CAS:26839-75-8
Purity:0.99 Package:5KG;1KG;25KG PRICE quotation Remarks:Factory stock, quality assurance, price concessions
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-188-71490254
Email: peter@hubeijusheng.com
Products Intro: Product Name:(S)-timolol (anhydrous)
CAS:26839-75-8
Purity:99% Package:5KG;1KG Remarks:C13H24N4O3S
Company Name: LGM Pharma  
Tel: 1-(800)-881-8210
Email: inquiries@lgmpharma.com
Products Intro: Product Name:TiMolol
CAS:26839-75-8
Purity:Typically NLT 98%
Company Name: Beijing HuaMeiHuLiBiological Chemical   
Tel: 010-56205725;010-86181995
Email: waley188@sohu.com
Products Intro: Product Name:tiMolol
CAS:26839-75-8
Purity:99% Package:25kg
Timolol Basic information
Product Name:Timolol
Synonyms:s-(-)-3-(3-tert-butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole;TimololMaleate26921-17-5/Base;(-)-S-Timolol;(S)-Timolol;2-Propanol, 1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-, (S)-(-)- (8CI);2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)- (9CI);2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (S)-;l-Timolol
CAS:26839-75-8
MF:C13H24N4O3S
MW:316.42
EINECS:248-032-6
Product Categories:Timolol
Mol File:26839-75-8.mol
Timolol Structure
Timolol Chemical Properties
pkapKa ~9.2(H2O t = 25.0) (Uncertain)
CAS DataBase Reference26839-75-8(CAS DataBase Reference)
EPA Substance Registry System2-Propanol, 1-[(1,1-dimethylethyl)amino]- 3-[[4-(4-morpholinyl)-1,2, 5-thiadiazol-3-yl]oxy]-, (2S)-(26839-75-8)
Safety Information
Hazardous Substances Data26839-75-8(Hazardous Substances Data)
Timolol Usage And Synthesis
UsesBetimol(Sanofi Winthrop).
Contact allergensTimolol was implicated in allergic contact dermatitis due to beta-blocker agents in eyedrops.
MetabolismTimolol (Timoptic) is almost completely absorbed from the gastrointestinal tract. Peak plasma levels occur 2 to 4 hours after oral administration; the plasma halflife of timolol is approximately 5.5 hours.The extensive tissue distribution of timolol into lung, liver, and kidney is similar to that of other -blockers. Approximately 70% of the drug is excreted in the urine within 24 hours, mostly as highly polar unconjugated metabolites. Only 6% of an administered dose is recovered in the feces. Although timolol is approved for the topical treatment of elevated intraocular pressure, there is limited information about its pharmacokinetics following administration by this route.The drug apparently can reach the systemic circulation after intraocular instillation, but plasma levels are only about 7% of those achieved in the aqueous humor.
Timolol Preparation Products And Raw materials
Tag:Timolol(26839-75-8) Related Product Information
TIMOLOL MALEATE EP STANDARD TIMOLOL-N/H dl-Timolol maleate 3-Chloro-4-Mopholino-1,2,5-Thiadiazol (intermediate of timolol maleate) (R)-TIMOLOL Racemic timolol,(+/-)-Timolol-d5 Maleate,rac Timolol-d5 Maleate d-Timolol Sucrose benzoate TIMOLOL MALEATE USP,(S)-TIMOLOL MALEATE,TIMOLOL HYDROGENMALEATE,TIMOLOL MALEATE SALT,TIMOLOL MALEATE 1,2,5-THIADIAZOL-3-OL 4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL Timolol DI-TERT-BUTYL ETHER Dimethomorph Moroxydine Moroxydine hydrochloride 2-Mercapto-5-methyl-1,3,4-thiadiazole 2,1,3-Benzothiadiazole