| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
|
| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:(±)-Decanoylcarnitine chloride
CAS:14919-36-9
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
|
| Company Name: |
EMMX Biotechnology LLC
|
| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:(±)-Decanoylcarnitine chloride
CAS:14919-36-9
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:(±)-Decanoylcarnitine chloride
CAS:14919-36-9
Purity:≥98% by HPLC Remarks:Homolog of acetylcarnitine chloride and (±)-Acetylcarnitine chloride is a weak AChR (cholinergic) agonist.
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:(+/-)-Decanoylcarnitinechloride
CAS:14919-36-9
Purity:NULL Package:100mg;50mg Remarks:NULL
|
|
| | DL-DECANOYLCARNITINE CHLORIDE Basic information |
| | DL-DECANOYLCARNITINE CHLORIDE Chemical Properties |
| storage temp. | −20°C | | solubility | <35.19mg/ml in H2O | | form | solid | | color | White | | Water Solubility | Soluble to 100 mM in water |
| | DL-DECANOYLCARNITINE CHLORIDE Usage And Synthesis |
| Chemical Properties | White crystalline powder | | Biological Activity | (±)-decanoylcarnitine chloride is an agonist for cholinergic and a homolog of acetylcarnitine chloride (cat no. b6273).acetylcholine receptor (achr) is an integral membrane protein receptor for acetylcholine. there are two kinds of achrs: nicotinic acetylcholine receptors and muscarinic acetylcholine receptors.(±)-decanoylcarnitine chloride is a cholinergic agonist and an intermediate in lipid metabolism [1]. in retinal ganglion cells, acetylcarnitine and acetylcholine inhibited gabaergic responses to exogenous gaba and gabaergic inhibitory postsynaptic currents [2].in dogs with coronary ligation, (-)-carnitine chloride (lcc) (300 mg/kg) and acetyl (-)-carnitine chloride (alcc) (300 mg/kg) inhibited the ventricular arrhythmia. also, lcc and alcc improved oxidative phosphorylation rate and the mitochondrial function [1]. in the mouse hot plate test, acetyl-l-carnitine (alcar) (100 mg/kg) exhibited analgesia. while, u-73122 and neomycin (the phospholipase c (plc) inhibitors) blocked the increase of the pain threshold induced by alcar. licl that impairing phosphatidylinositol synthesis antagonized the antinociception in a dose-dependent way. pma and pdbu (pkc activators) blocked the increase of the pain threshold in a dose-dependent way. these results suggested that alcar analgesia required the participation of the plc-ip3 pathway [3]. |
| | DL-DECANOYLCARNITINE CHLORIDE Preparation Products And Raw materials |
|