isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate 基本信息
| 中文名称 | isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate |
|---|---|
| 中文同义词 | 替诺福韦拉酚氨酯杂质08;替诺福韦艾拉酚胺非对映异构体(RRR);(S)-2-氨基丙酸异丙酯盐酸盐 L-丙氨酸异丙酯盐酸盐(R)-丙胺酸异丙酯2-{(R)-[((R)-1-(6-氨基-9H-嘌呤-9-基)-1-甲基乙氧基]甲基}-苯氧基磷酰基;替诺福韦艾拉酚胺杂质08;替诺福韦杂质41;替诺福韦艾拉酚胺酯杂质7;替诺福韦拉酚氨酯杂质7;TAF-IM-C(9-{(R)-2-[({[(R)-1-(异丙基氧基羰基)乙基]氨基}-苯氧基磷酰基)甲氧基]丙基}腺嘌呤) |
| 英文名称 | isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate |
| 英文同义词 | isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate;isopropyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate;Tenofovir Alafenamide Impurity 16;isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate fumarate;D-Alanine, N-[(R)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester;isopropyl(((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate |
| CAS号 | 2053424-88-5 |
| 分子式 | C21H29N6O5P |
| 分子量 | 476.47 |
| EINECS号 | |
| 相关类别 | 替诺福韦拉酚氨酯杂质;对照品-杂质对照品;替诺福韦艾拉酚胺杂质;045-替诺福韦拉酚氨酯 |
| Mol文件 | 2053424-88-5.mol |
| 结构式 |  |
isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate 性质
| 熔点 | 134 - 138°C |
|---|---|
| 沸点 | 640.4±65.0 °C(Predicted) |
| 密度 | 1.39±0.1 g/cm3(Predicted) |
| 储存条件 | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度 | 可溶于氯仿（轻微）、甲醇（轻微、超声处理） |
| 酸度系数(pKa) | 4.21±0.10(Predicted) |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
| 稳定性 | 吸湿性 |