2'-F-2'-ARA-BZ-DC 亚磷酰胺单体
| 中文名称 | 2'-F-2'-ARA-BZ-DC 亚磷酰胺单体 |
|---|---|
| 中文同义词 | 2'-F-2'-ARA-BZ-DC 亚磷酰胺单体;2'-F-2'-ARA-DC(BZ) 亚磷酰胺单体;2'-氟-阿糖DC(BZ)亚磷酰胺单体;N4-苯甲酰基-5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-氟-2'-脱氧阿糖胞苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯];2'-F-ANA-DC(BZ) 亚磷酰胺单体;N4-BZ-5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-氟-2'-脱氧阿糖胞苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯];(2R,3R,4S,5R)-5-(4-苯甲酰氨基-2-氧代嘧啶-1(2H)-基)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-氟四氢呋喃-3-基 (2-氰基乙基) 二异丙基亚磷酰胺;化合物 2'-FLUORO-2'-DEOXY-ARA-C(BZ)-3'-PHOSPHORAMIDITE |
| 英文名称 | 2'-Fluoro-2'-deoxy-ara-C-3'-phosphoramidite |
| 英文同义词 | 2'-Fluoro-2'-deoxy-ara-C-3'-phosphoramidite;2'-F-2'-ara-Bz-dC Phosphoramidite;N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro--D-arabinouridine-3'-CED-phosphoramidite;N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-beta-D-arabinouridine-3'-CEN-phosphoramidite;2'-F-dC(Bz)-ANA-CE Phosphoramidite;N4-Benzoyl-2'-fluoro-5'-O-DMT-2'-arabinofuranosyl-deoxycytidine phosphoramidite;2'-F-2'-ara-N4-Bz-dC phosphoramidite;Benzamide, N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]- |
| CAS号 | 1404463-12-2 |
| 分子式 | C46H51FN5O8P |
| 分子量 | 851.91 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1404463-12-2.mol |
| 结构式 |  |
2'-F-2'-ARA-BZ-DC 亚磷酰胺单体 性质
| 溶解度 | DMSO: Sparingly Soluble: 1-10 mg/ml Ethanol: Sparingly Soluble: 1-10 mg/ml |
|---|---|
| 酸度系数(pKa) | 8.50±0.20(Predicted) |
| 形态 | Solid |
| 颜色 | White to off-white |
2'-F-2'-ARA-BZ-DC 亚磷酰胺单体 是一种胞嘧啶核苷类似物。胞苷类似物具有抑制 DNA 甲基转移酶的机制 (如 Zebularine，HY-13420)，具有潜在的抗代谢和抗肿瘤活性。