3-[[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]benzamide
| 中文名称 | 3-[[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]benzamide |
|---|---|
| 中文同义词 | 化合物 T10124;化合物ANTIULCER AGENT 1 |
| 英文名称 | 3-[[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]benzamide |
| 英文同义词 | 3-[[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]benzamide;Antiulcer Agent 1;Benzamide, 3-[[2-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]-;Antiulcer Agent 1,inhibit,Inhibitor,Antiulcer Agent-1,Antiulcer Agent1 |
| CAS号 | 76001-09-7 |
| 分子式 | C19H23N3O4 |
| 分子量 | 357.40362 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 76001-09-7.mol |
| 结构式 | ![3-[[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]benzamide 结构式](CAS/20180528/GIF/76001-09-7.gif) |
3-[[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]benzamide 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
Antiulcer Agent 1 是 2-(3,4-dimethoxyphenyl)ethylamine 的衍生物，是一种口服剂，处于新药开发的探索阶段。
The hydrochloride form shows incompatibility with the excipients used for oral dosage forms. There are several crystal forms of the free base, namely, alpha-anhydrate, beta-anhydrate, monohydrate, and trihydrate. The trihydrate form is unstable. The degree of crystallinity of the beta-anhydrate form is difficult to control. The monohydrate form is difficult to manufacture with constant quality. The serum levels of the compounds in rats are almost related to the dissolution rates in the JP 1st disintegration medium from the discs. The serum level of alpha-anhydrate is the lowest.