5α-Pregnane-3β,6α-diol-20-one
| 中文名称 | 5α-Pregnane-3β,6α-diol-20-one |
|---|---|
| 中文同义词 | 5Α-PREGNANE-3Β,6Α-DIOL-20-ONE;化合物5Α-PREGNANE-3Β,6Α-DIOL-20-ONE |
| 英文名称 | 5α-Pregnane-3β,6α-diol-20-one |
| 英文同义词 | 5α-Pregnane-3β,6α-diol-20-one;5α-Pregnane-3β,6α-diol-20-one;5αPregnane3β,6αdiol20one,5α Pregnane 3β,6α diol 20 one,inhibit,Inhibitor |
| CAS号 | 21853-11-2 |
| 分子式 | C21H34O3 |
| 分子量 | 334.49 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 21853-11-2.mol |
| 结构式 |  |
5α-Pregnane-3β,6α-diol-20-one 性质
| 熔点 | 202-203 °C |
|---|---|
| 沸点 | 469.7±30.0 °C(Predicted) |
| 密度 | 1.117±0.06 g/cm3(Predicted) |
| 酸度系数(pKa) | 14.72±0.70(Predicted) |
5α-Pregnane-3β,6α-diol-20-one 是一种促进有丝分裂的 progesterone 代谢物，可于血清不足时雄性激素反应的前列腺素癌细胞中产生。
Progesterone is converted to 5α-pregnane-3β,6α-diol-20-one in human fibroblasts. Pregnenolone and progesterone are avidly metabolized to 5α-pregnan-3β,6α-diol-20-one in the C4.2 cell line, with nearly complete conversions at 24 h and 18 h, respectively. Preferential 5α-pregnan-3β,6α-diol-20-one formation from early steroid precursors is independent of CYP17A1 but rather relies on 3β-HSD activity.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-109564 | 5α-Pregnane-3β,6α-diol-20-one | 1 mg | 571元 | |
| 2024/01/25 | HY-109564 | 5α-Pregnane-3β,6α-diol-20-one 5α-Pregnane-3β,6α-diol-20-one | 21853-11-2 | 5mg | 1500元 |