Gastrofensin AN 5 free base
中文名称 | Gastrofensin AN 5 free base |
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中文同义词 | 化合物 T11367 |
英文名称 | Gastrofensin AN 5 free base |
英文同义词 | Gastrofensin AN 5 free base;Carbamic acid, [4-(4-chlorophenyl)-1,2,3,4-tetrahydro-2-methyl-8-isoquinolinyl]-, ethyl ester (9CI) |
CAS号 | 89845-16-9 |
分子式 | C19H21ClN2O2 |
分子量 | 344.84 |
EINECS号 | |
相关类别 | |
Mol文件 | 89845-16-9.mol |
结构式 |
Gastrofensin AN 5 free base 性质
储存条件 | Store at -20°C |
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溶解度 | 溶于二甲基亚砜 |
Gastrofensin AN 5 supresses the formation of ulcers in all experimental models. From the broad pharmacological studies of Gastrofensin AN 5 on this model it can be seen that even a dose of 0.100 mg/kg has a high antiulcer activity. The increase of the dose leads to a regular increase of the antiulcer activity, the highest suppression of the ulcer index being reaches at a dose of 1 mg/kg (86.15%). The comparative studies with Ranitidine and Cimetidine on the same experimental models of gastric ulcers show that Gastrofensin AN 5 possesses an antiulcer activity many times higher than that of the above-mentioned drugs.