2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine
| 中文名称 | 2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine |
|---|---|
| 中文同义词 | 化合物 2'-DEOXY-2'-FLUORO-6-S-METHYL-6-THIO-ARABINO-INOSINE |
| 英文名称 | 2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine |
| 英文同义词 | 2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine;9H-Purine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-(methylthio)-;2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-arabino-inosine;(2R,3R,4S,5R)-4-fluoro-2-(hydroxymethyl)-5-(6-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3-ol |
| CAS号 | 109304-12-3 |
| 分子式 | C11H13FN4O3S |
| 分子量 | 300.31 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 109304-12-3.mol |
| 结构式 |  |
2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine 性质
| 熔点 | 152-153 °C |
|---|---|
| 沸点 | 594.4±60.0 °C(Predicted) |
| 密度 | 1.80±0.1 g/cm3(Predicted) |
| 酸度系数(pKa) | 12.58±0.70(Predicted) |
2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-arabino-inosine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。