商陆皂苷甲
中文名称 | 商陆皂苷甲 |
---|---|
中文同义词 | 商陆皂甙甲;商陆皂苷甲;商陆皂甙A;商陆种苷A;商陆皂甙;商陆皂苷A;商陆皂苷甲(标准品);商陆皂甙A、商陆种苷A、商陆皂甙甲 |
英文名称 | Esculentoside A |
英文同义词 | ESCULENTOSIDE A;Esculentoside;(2b,3b,4a,20b)-3-((4-O-beta-D-Glucopyranosyl-beta-D-xylopyranosyl)oxy)-2,23-dihydroxyolean-12-ene-28,29-dioic acid 29-methyl ester;Phytolaccasaponin E;Esculentoside A, 98%, from Phytolacca acinosa Roxb.;Olean-12-ene-28,29-dioic acid, 3-[(4-O-β-D-glucopyranosyl-β-D-xylopyranosyl)oxy]-2,23-dihydroxy-, 29-methyl ester, (2β,3β,4α,20β)-;Esculentoside A USP/EP/BP |
CAS号 | 65497-07-6 |
分子式 | C42H66O16 |
分子量 | 826.96 |
EINECS号 | |
相关类别 | 植提标准品;对照品;中药对照品;标准品;植物提取物;天然产物;标准品-中药标准品;标准品,对照品;Saponins;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;标准品 -中药标准品;分析试剂-对照品;天然植物提取物 |
Mol文件 | 65497-07-6.mol |
结构式 |
商陆皂苷甲 性质
熔点 | >192°C (dec.) |
---|---|
沸点 | 936.7±65.0 °C(Predicted) |
密度 | 1.42±0.1 g/cm3(Predicted) |
储存条件 | Hygroscopic, -20°C Freezer, Under inert atmosphere |
溶解度 | 可溶于DMSO(少许)、甲醇(少许) |
酸度系数(pKa) | 4.39±0.70(Predicted) |
形态 | 固体 |
颜色 | 淡黄色低 |
稳定性 | 吸湿性 |
Esculentoside A (0-10 μM; 24 hours) reduced the release of TNF concentration in primed macrophages .
Esculentoside A (EsA) (intraperitoneal injection; 20 mg/kg; once a day; 4 weeks) plays significant roles in the treatment of BXSB mice through modulation of inflammatory cytokines, inhibition of renal cell proliferation and induction of apoptosis . Esculentoside A (EsA) (injected intraperitoneally; 5, 10 and 20 mg/kg; once a day; 7 days) dose-dependently decreases the TNF, IL-1 and IL-6 levels in the sera of mice following LPS challenge.
Animal Model: | BXSB mice |
Dosage: | 20 mg/kg |
Administration: | Intraperitoneal injection; 20 mg/kg; once a day; 4 weeks |
Result: | Alleviated the renal damage of LN. |
安全信息
安全说明 | 24/25 |
---|---|
海关编码 | 29389090 |
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024/01/25 | HY-N0632 | Esculentoside A | 1 mg | 304元 | |
2024/01/25 | HY-N0632 | 商陆皂苷甲 Esculentoside A | 65497-07-6 | 5mg | 800元 |