| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Afurolol;Afurolol
CAS:65776-67-2
Purity:98% Package:5 mg
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| Company Name: |
Leancare Ltd.
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| Tel: |
+33 962096793 |
| Email: |
enquiry@leancare.co.uk |
| Products Intro: |
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| | Afurolol Basic information |
| Product Name: | Afurolol | | Synonyms: | Afurolol;7-[3-(tert-Butylamino)-2-hydroxypropoxy]isobenzofuran-1(3H)-one;1(3H)-Isobenzofuranone, 7-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-;Afurololum | | CAS: | 65776-67-2 | | MF: | C15H21NO4 | | MW: | 279.33154 | | EINECS: | | | Product Categories: | | | Mol File: | 65776-67-2.mol |  |
| | Afurolol Chemical Properties |
| | Afurolol Usage And Synthesis |
| Originator | Afurolol ,ZYF Pharm Chemical | | Manufacturing Process | A mixture of 18.0 g (0.12 mole) 7-hydroxyphthalide, 180.0 g of 1-chloro-2,3-
epoxypropane (2 moles) and 0.5 ml of piperidine is heated at 100°C for about
5 h and then the unreacted 1-chloro-2,3-epoxypropane is distilled off in
vacuum to yield 12.0 g (48%) of 7-(2,3-epoxypropoxy)phthalide, melting
point 88°-90°C, (crystallized successively from methanol and ethyl acetate).
The 7-(2,3-epoxypropoxy)phthalide is dissolved in methanol and t-butylamine
are added to the solution at about 20°C. The solution is allowed to stand overnight and, the mixture is evaporated in vacuum and the residue is dried
to give 7-(2-hydroxy-3-t-butylamino-propoxy)phthalide. | | Therapeutic Function | Beta-adrenergic blocker |
| | Afurolol Preparation Products And Raw materials |
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