IBAFLOXACINE
| 中文名称 | IBAFLOXACINE |
|---|---|
| 中文同义词 | 伊巴沙星;化合物 T12649 |
| 英文名称 | Ibafloxacine |
| 英文同义词 | Ibafloxacine;S 25930;6,7-Dihydro-9-fluoro-5,8-dimethyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid;9-Fluoro-6,7-dihydro-5,8-dimethyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid;R835;1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5,8-dimethyl-1-oxo- |
| CAS号 | 91618-36-9 |
| 分子式 | C15H14FNO3 |
| 分子量 | 275.27 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 91618-36-9.mol |
| 结构式 |  |
IBAFLOXACINE 性质
| 熔点 | 269-272° |
|---|---|
| 沸点 | 477.5±45.0 °C(Predicted) |
| 密度 | 1.40±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 5.71±0.40(Predicted) |
Ibafloxacine (R835) 是一种专门用于兽医用途的氟喹诺酮类抗生素。
The pharmacokinetic behavior of Ibafloxacin is studied after intravenous administration of a single dose of 15 mg/kg to 6 healthy lactating goats. Plasma concentrations of Ibafloxacin are determined by high-performance liquid chromatography with fluorescence detection. After IV injection Ibafloxacin shows very rapid initial distribution, with a mean half-life of 0.35 h, follows by slower elimination, with a mean half-life of 3.76 h. The elimination half-life of Ibafloxacin after oral administration has been reported to be 3.83 h in dogs and 3.00 h in cats.