- H-L-Tyr-Oet.Hcl
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- $0.00 / 1kg
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2024-04-25
- CAS:4089-07-0
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
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| | L-Tyrosine Ethyl Ester Hydrochloride Basic information |
| | L-Tyrosine Ethyl Ester Hydrochloride Chemical Properties |
| Melting point | 166-170 °C | | alpha | [α]D20 +26～+30° (c=5, C2H5OH) | | refractive index | -6.5 ° (C=2, H2O) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | powder to crystal | | color | White to Almost white | | Water Solubility | Soluble in water (3.685e+005 mg/L @ 25°C (est.)). | | BRN | 4725904 | | InChIKey | BQULAXAVRFIAHN-PPHPATTJSA-N | | LogP | 1.060 (est) | | CAS DataBase Reference | 4089-07-0(CAS DataBase Reference) |
| | L-Tyrosine Ethyl Ester Hydrochloride Usage And Synthesis |
| Chemical Properties | White to off-white microcrystalline powder | | Uses | L-Tyrosine Ethyl Ester Hydrochloride is used as a medical and organic intermediate and as an important amino protective agent. It is also used to introduce t-Boc protect gene. | | Application | Papain is also used for synthesizing poly(L-tyrosine) and poly(L-glutamic acid) using L-tyrosine ethyl ester hydrochloride and L-glutamic acid diethyl ester hydrochloride as the substrates, respectively. The protease-catalyzed copolymerization of amino acids is first achieved by papain using L-glutamic acid ester and various amino acid esters as substrates.
A mixture of L-tyrosine ethyl ester hydrochloride, the appropriate acid anhydri-des, triethylamine and dry tetrahydrofuran, was warmed for an hour in an atmosphere of nitrogen. After removing the amine salt, Ic and Id became crystalline on standing overnight in the cold. | | Preparation | synthesis of L-Tyrosine Ethyl Ester Hydrochloride: Esterification of 25 g. ol L-tyrosine (0.014 mole) with ethanolic hydrogen chloride gave 24.1 g. of L-tyrosine ethyl ester hydrochloride (80%). Liberation of the ester by slurrying the hydrochloride in chloroform rollowed by the addition of chloroform saturated with ammonia, removal of the ammonium chloride by filtration and evaporation of the chloroform gave 19.4 g. of L-tyrosine ethyl ester (67%), m.p. 106-108 ° . |
| | L-Tyrosine Ethyl Ester Hydrochloride Preparation Products And Raw materials |
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