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| | safracin B Basic information |
| Product Name: | safracin B | | Synonyms: | safracin B;2-Amino-N-[(6,7,9,10,13,14,14a,15-octahydro-1,7-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-epimino-5H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]propionamide;Antibiotic Y 16482-alpha;Antibiotic EM 5519;Propanamide, 2-amino-N-[[(6S,7S,9R,14aS,15R)-6,7,9,10,13,14,14a,15-octahydro-1,7-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-, (2S)- | | CAS: | 87578-99-2 | | MF: | C28H36N4O7 | | MW: | 540.61 | | EINECS: | | | Product Categories: | | | Mol File: | 87578-99-2.mol |  |
| | safracin B Chemical Properties |
| Boiling point | 755.1±60.0 °C(Predicted) | | density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO (up to 20 mg/ml) | | form | solid | | pka | 9.75±0.70(Predicted) | | color | Yellow-green | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| | safracin B Usage And Synthesis |
| Description | Safracin B (87578-99-2) is a novel antibiotic of the saframycin family produced by?Pseudomonas fluorescens.1?Safracin B displays antitumor activity against L1210 and P388 leukemias and B16 melanoma. Compared with safracin A, the toxic and effective doses were much lower. Safracin B also prolonged the life of tumor-bearing mice to a greater extent than safracin A.2 | | Uses | Safracin B is a new antibiotics from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B is an antibiotic that exhibits anti-tumor properties. | | References | 1) Ikeda?et al.?(1983),?Safracins, new antitumor antibiotics. I. Producing organism, fermentation and isolation; J. Antibiot. Tokyo,?36?1279
2) Okumoto?et al. (1985),?Activity of safracins A and B, heterocyclic quinone antibiotics, on experimental tumors in mice; J. Antibiot.Tokyo,?38?767 |
| | safracin B Preparation Products And Raw materials |
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