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| | (R)-1-Boc-3-methylpiperazine Basic information |
| | (R)-1-Boc-3-methylpiperazine Chemical Properties |
| Melting point | 40-45 °C | | Boiling point | 268.7±15.0 °C(Predicted) | | density | 0.997±0.06 g/cm3(Predicted) | | Fp | 223 °F | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 8.52±0.40(Predicted) | | form | Crystalline Powder | | color | White | | optical activity | [α]/D +16±2°, c = 1 in dioxane | | InChIKey | FMLPQHJYUZTHQS-MRVPVSSYSA-N | | CAS DataBase Reference | 163765-44-4(CAS DataBase Reference) |
| | (R)-1-Boc-3-methylpiperazine Usage And Synthesis |
| Chemical Properties | White solid | | Uses | (R)-4-Boc-2-methylpiperazine is a reagent used in organic synthesis. Used in the synthesis of orally bioavailable inhibitors of 11-β-hydroxysteroid. (R)-4-Boc-2-methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | | Synthesis | To a solution of (R)-methylpiperazine (400 mg) in dichloromethane (20 mL) at 0 ℃ was added di-tert-butyl dicarbonate (871 mg). The reaction was stirred at room temperature for 4 h and then quenched with water (20 mL), followed by extraction into dichloromethane (2 x 40 mL). The combined organics were washed with saturated aqueous brine solution (40 mL), dried (MgSO4), and concentrated to give (R)-1-Boc-3-methylpiperazine as a white solid (669 mg, 84%).
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| | (R)-1-Boc-3-methylpiperazine Preparation Products And Raw materials |
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