| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:Eticlopride hydrochloride;3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)Methyl]-6-hydroxy-2-Methoxy-benzaMidehydrochloride
CAS:97612-24-3
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:S-(-)-Eticlopride hydrochloride
CAS:97612-24-3
Purity:>=98% (HPLC), powder Package:25MG Remarks:E101-25MG
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| | FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Basic information |
| Product Name: | FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride | | Synonyms: | S(-)-ETICLOPRIDE HYDROCHLORIDE (POTENT A ND SELECTIVE D2 DOPAMINE;FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride;3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamidehydrochloride;Eticlopride hydrochl;Benzamide,3-chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-6-hydroxy-2-methoxy-,hydrochloride (1:1);(2S)-2-{[(3-chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl}-1-ethylpyrrolidinium chloride;Eticlopride HCl | | CAS: | 97612-24-3 | | MF: | C17H26Cl2N2O3 | | MW: | 377.31 | | EINECS: | | | Product Categories: | | | Mol File: | 97612-24-3.mol | ![FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Structure](CAS/20211123/GIF/97612-24-3.gif) |
| | FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Chemical Properties |
| Melting point | 144-146 °C(Solv: acetone (67-64-1)) | | storage temp. | Desiccate at RT | | solubility | H2O: soluble >10mg/mL | | form | powder | | color | off-white | | optical activity | [α]27/D 7.2°, c = 0.3 in methanol(lit.) | | Water Solubility | Soluble to 100 mM in water |
| WGK Germany | 3 | | RTECS | CV2450000 |
| | FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Usage And Synthesis |
| Uses | Dopamine receptor antagonist | | Uses | S-(?)-Eticlopride hydrochloride has been used in astrocyte-neuron coculture and functional magnetic resonance imaging (fMRI) experiments. | | Biological Activity | Selective dopamine D 2 /D 3 receptor antagonist (K i values are 0.50 and 0.16 nM respectively). Antipsychotic. | | Biochem/physiol Actions | Potent and selective D2 dopamine receptor antagonist. Eticlopride is highly specific for DAD2?receptors than pimozide or haloperidol. The gene encoding the D2 dopamine receptor (DRD2) is linked with a several disorders including Parkinson′s disease, schizophrenia, and susceptibility to alcoholism. | | storage | room temperature (desiccate) |
| | FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Preparation Products And Raw materials |
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