触角肽
| 中文名称 | 触角肽 |
|---|---|
| 中文同义词 | 黑腹果蝇触足肽 |
| 英文名称 | Penetratin |
| 英文同义词 | Antennapedia;L-Lysine, L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl- |
| CAS号 | 188842-14-0 |
| 分子式 | C104H168N34O20S |
| 分子量 | 2246.73 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 188842-14-0.mol |
| 结构式 |  |
触角肽 性质
| 密度 | 1.44±0.1 g/cm3(Predicted) |
|---|
Antennapedia Peptide 是由 16 个氨基酸残基组成的多肽，来源于果蝇转录因子 Antennapedia 的 60 个氨基酸序列的同源域，它同时是一种穿膜肽。
Antennapedia (Antp)-SMCC-cytochrome c conjugate (5 μg/mL) activates caspase-dependent apoptosis of HeLa cells. The Antp-SMCC-cytochrome c conjugate reduces the clonogenic survival of Hela cells, and inhibits clonogenic survival. ANTP-SmacN7 fusion protein can transduce and accumulate in cells, while SmacN7 alone cannot. ANTP-SmacN7 fusion proteins have a radiation-sensitising effect on EC109 cells. ANTP-SmacN7 combined with radiation does not promote further increases in caspase-3 protein expression, it increases the levels of cleaved caspase-3.