胆甾烯基豆蔻酸酯
中文名称 | 胆甾烯基豆蔻酸酯 |
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中文同义词 | 肉豆蔻酸胆固醇酯;胆固醇肉豆蔻酸酯,液晶;肉豆蔻酸胆固醇;胆固醇豆蔻酸酯;豆蔻酸胆固醇酯;胆甾烯基豆蔻酸酯;胆甾醇豆蔻酸酯;胆固醇肉豆蔻酸?, >98% |
英文名称 | Cholesteryl myristate |
英文同义词 | 3β-Hydroxy-5-cholestene 3-tetradecanoate, 5-Cholesten-3β-ol 3-tetradecanoate, Cholesteryl tetradecanoate;Cholest-5-en-3β-ol tetradecanoate;Cholesterol=tetradecanoate;Myristic acid 3β-cholesteryl ester;Tetradecanoic acid 3β-cholesteryl ester;Cholesteryl myristate,97%,liquid crystal;MYRISTIC ACID CHOLESTEROL ESTER;(3β)-cholest-5-en-3-yltetradecanoate |
CAS号 | 1989-52-2 |
分子式 | C41H72O2 |
分子量 | 597.01 |
EINECS号 | 217-867-8 |
相关类别 | 合成;有机中间体;Steroids;Cholesteryl Compounds (Liquid Crystals);Functional Materials;Liquid Crystals & Related Compounds |
Mol文件 | 1989-52-2.mol |
结构式 | ![]() |
胆甾烯基豆蔻酸酯 性质
熔点 | 84 °C |
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沸点 | 589.77°C (rough estimate) |
密度 | 0.9309 (rough estimate) |
折射率 | 1.5250 (estimate) |
储存条件 | Sealed in dry,2-8°C |
溶解度 | 氯仿(微溶)、己烷(微溶) |
形态 | 结晶固体 |
颜色 | 白色至米白色 |
LogP | 16.656 (est) |
CAS 数据库 | 1989-52-2(CAS DataBase Reference) |
NIST化学物质信息 | Cholesteryl myristate(1989-52-2) |
EPA化学物质信息 | Cholest-5-en-3-ol (3.beta.)-, tetradecanoate (1989-52-2) |
Human Endogenous Metabolite
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Mesenchymal stem cells (MSCs) transfected by the Id1 promoter reporter construct, cholesterol myristate increases the activity of Id1 promoter. Cholesterol myristate inhibits the apoptosis of MSCs induced by serum-free. Cholesterol myristate increases the expression of Id1 and its target gene bcl-x/l in MSCs treated with serum-free. Moreover, noggin, a BMP antagonist, reduces the anti-apoptotic effects of cholesterol myristate. Cholesterol myristate inhibits the apoptosis of PC12 cells induced in serum-free condition. Cholesterol myristate significantly increases the expression of BMP4, BMPRIA, p-Smad1/5/8, Id1 and its antiapoptotic target gene Bcl-xL in PC12 cells treated in serum-free condition.