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Roxarsone

Roxarsone Basic information
Product Name:Roxarsone
Synonyms:2-NITROPHENOL-4-ARSONIC ACID;4-HYDROXY-3-NITROBENZENENEARSONIC ACID;4-HYDROXY-3-NITROBENZENEARSONIC ACID;4-HYDROXY-3-NITROPHENYLARSONIC ACID;4-Hydroxy-3-nitrobenzenearsonic acid,98%;Roxarsone (200 mg);Roxasone;p-Hydroxy-M-nitrophenylarsonic Acid
CAS:121-19-7
MF:C6H6AsNO6
MW:263.04
EINECS:204-453-7
Product Categories:Pharmaceutical intermediates;MERTHIOLATE;Organometallics;As (Arsenic) Compounds;Classes of Metal Compounds;Semimetal Compounds
Mol File:121-19-7.mol
Roxarsone Structure
Roxarsone Chemical Properties
Melting point ≥300 °C(lit.)
Boiling point 537.3±60.0 °C(Predicted)
density 2.02 g/cm3
storage temp. 0-6°C
solubility insoluble in Ether
pka3.51±0.10(Predicted)
form liquid
color Light yellow to Yellow
Water Solubility <0.1 g/100 mL at 23 ºC
Merck 14,8273
BRN 1976533
Stability:Hygroscopic
InChIKeyXMVJITFPVVRMHC-UHFFFAOYSA-N
CAS DataBase Reference121-19-7(CAS DataBase Reference)
EPA Substance Registry SystemRoxarsone (121-19-7)
Safety Information
Hazard Codes T,N
Risk Statements 23/25-50/53
Safety Statements 20/21-28-45-60-61
RIDADR UN 3465 6.1/PG 2
WGK Germany 3
RTECS CY5250000
HazardClass 6.1(b)
PackingGroup III
HS Code 29319090
Hazardous Substances Data121-19-7(Hazardous Substances Data)
ToxicityLD50 in rats, chickens (mg/kg): 155, 110-123 orally; 66, 34 i.p. (Kerr)
MSDS Information
ProviderLanguage
Roxarsone English
SigmaAldrich English
ACROS English
Roxarsone Usage And Synthesis
Chemical PropertiesBEIGE-BROWN FINE CRYSTALLINE POWDER
Usesantiinfective, preservative
UsesFormerly in manufacture of arsphenamines; as reagent for zirconium.
Uses4-Hydroxy-3-nitrophenylarsonic Acid is used as a feed additive for chicken to aid in the prevention of coccidiosis caused by E[imeria] tenella and E. necatrix.
DefinitionChEBI: An organoarsonic acid where the organyl group is 4-hydroxy-3-nitrophenyl.
General DescriptionPale yellow crystals or light tan powder.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileMay be sensitive to light and elevated temperatures on long-term storage. Roxarsone puffs up and deflagrates on heating. Incompatible with strong oxidizers and strong acids. Forms mono-, di-, and trisodium salts.
HazardToxic by ingestion, highly toxic.
Fire HazardFlash point data are not available for Roxarsone ; however, Roxarsone is probably combustible.
Purification MethodsIt crystallises from water and is used for the spectroscopic detection of Zn. [Beilstein 16 II 468, 16 III 1073, 16 IV 1188.]
Roxarsone Preparation Products And Raw materials
Raw materialsHydrochloric acid-->Nitric acid-->Sodium nitrite-->4-Aminophenol-->4-Aminophenylarsonic acid-->PH TEST STRIPS PH RANGE 0-14.0-->4-HYDROXYPHENYLARSONIC ACID
Preparation ProductsACETARSONE
Tag:Roxarsone(121-19-7) Related Product Information
4-Hydroxybenzaldehyde 4-Hydroxybenzoic acid 4-Nitrobenzoic acid 4-Aminophenylarsonic acid Methylparaben 3-Nitroacetophenone 4-Methoxyphenol CHLOROPHOSPHONAZO III Sodium 3-nitrobenzenesulphonate Nitrobenzene 3-amino-4-hydroxyphenylarsonic acid Phenylarsine oxide Roxarsone PHENYLARSONIC ACID 4-HYDROXYPHENYLARSONIC ACID METHYLARSONIC ACID ARSENIC PENTOXIDE ARSINE