琥珀酰亚胺酯-十七聚乙二醇-琥珀酰亚胺酯
中文名称 | 琥珀酰亚胺酯-十七聚乙二醇-琥珀酰亚胺酯 |
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中文同义词 | 琥珀酰亚胺酯-十七聚乙二醇-琥珀酰亚胺酯 |
英文名称 | 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52-Heptadecaoxapentapentacontanedioic acid, 1,55-bis(2,5-dioxo-1-pyrrolidinyl) ester |
英文同义词 | 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52-Heptadecaoxapentapentacontanedioic acid, 1,55-bis(2,5-dioxo-1-pyrrolidinyl) ester;Bis-dPEG17-NHS ester;Di-NHS Ester-PEG17 |
CAS号 | 2221948-93-0 |
分子式 | C46 H80 N2 O25 |
分子量 | 1061.13 |
EINECS号 | |
相关类别 | PEG类产品-Activated molecular |
Mol文件 | 2221948-93-0.mol |
结构式 |
琥珀酰亚胺酯-十七聚乙二醇-琥珀酰亚胺酯 性质
沸点 | 921.6±75.0 °C(Predicted) |
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密度 | 1.25±0.1 g/cm3(Predicted) |
PEGs
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Alkyl/ether
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Cleavable
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PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.