异樱花亭
| 中文名称 | 异樱花亭 |
|---|---|
| 中文同义词 | 异樱花亭;5,7-二羟基-4'-甲氧基黄烷酮;异野樱素;异樱花亭苷;异樱花素;异樱花素,异樱花亭(异樱花亭苷);异野樱素,异樱花素;异樱花亭(标准品) |
| 英文名称 | ISOSAKURANETIN |
| 英文同义词 | 5,7-DIHYDROXY-4'-METHOXYFLAVANONE;ISOSAKURANETIN;(S)-2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone;ISOSAKURANETIN(P);5,7-DIHYDROXY-4''-METHOXYFLAVANONE hplc;ISOSAKURANETIN WITH HPLC;(2S)-5,7-Dihydroxy-4'-methoxyflavanone;(S)-2,3-Dihydro-2-(4-methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one |
| CAS号 | 480-43-3 |
| 分子式 | C16H14O5 |
| 分子量 | 286.28 |
| EINECS号 | 207-551-8 |
| 相关类别 | 对照品标准品;对照品;中药对照品;植物提取物;标准品;分析试剂标准品;对照品-中药对照品;黄酮;Flavanones;Flavonoids;标准品 -中药标准品;标准品，对照品 |
| Mol文件 | 480-43-3.mol |
| 结构式 |  |
异樱花亭 性质
| 熔点 | 193-194°C |
|---|---|
| 沸点 | 539.2±50.0 °C(Predicted) |
| 密度 | 1.370±0.06 g/cm3(Predicted) |
| 溶解度 | DMSO：125 mg/mL（436.64 mM；需要超声波和加热） |
| 形态 | 粉末 |
| 酸度系数(pKa) | 7.50±0.40(Predicted) |
| 颜色 | 白色 |
| LogP | 3.840 (est) |
Isosakuranetin stimulates melanin accumulation in a dose-dependent manner. In addition, Isosakuranetin at 30 μM gradually increases the expression of Tyr, TRP1, and TRP2 after 48 and 72 h. The MTT assay shows that Isosakuranetin decreases the number of cells at concentrations greater than 45 μM. Further analysis of trypan blue staining demonstrates that Isosakuranetin does not affect the viability of B16 melanocytes, but shows that Isosakuranetin decreases their proliferation rate. The tyrosinase activity of B16 melanocytes treated with 15 and 30 μM Isosakuranetin for 72 h is significantly increased by 2- and 3.2-fold, respectively, in comparison with that of the control cells.
Isosakuranetin dose-dependently increases the paw-withdrawal threshold within the dose range of 1.5 to 6 mg/kg. Post hoc analysis reveals that Isosakuranetin increases the paw-withdrawal threshold and statistical significance is seen at times 30 and 40 min for the dose of 3 mg/kg and 30 to 60 min for the dose of 6 mg/kg.
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-N2131 | Isosakuranetin | 1 mg | 457元 | |
| 2024/01/25 | HY-N2131 | 异樱花亭 Isosakuranetin | 480-43-3 | 5mg | 1950元 |