H-LEU-ARG-PRO-OH
| 中文名称 | H-LEU-ARG-PRO-OH |
|---|---|
| 中文同义词 | L-亮氨酰-L-精氨酰-L-脯氨酸;化合物LEUCYLARGINYLPROLINE |
| 英文名称 | H-LEU-ARG-PRO-OH |
| 英文同义词 | LHRH (7-9) SEQUENCE 2HCL;H-LEU-ARG-PRO-OH;H-LEU-ARG-PRO-OH 2HCL;LHRH 7-9 SEQUENCE;Leu-Arg-Pro;LRP;Leucylarginylproline;L-Proline,L-leucyl-L-arginyl- |
| CAS号 | 133943-59-6 |
| 分子式 | C17H32N6O4 |
| 分子量 | 384.47 |
| EINECS号 | |
| 相关类别 | 试剂盒-Elisa试剂盒 |
| Mol文件 | 133943-59-6.mol |
| 结构式 |  |
H-LEU-ARG-PRO-OH 性质
| 密度 | 1.39±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | -15°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 3.39±0.20(Predicted) |
Leucylarginylproline是血管紧张素转换酶 (ACE) 抑制剂，IC50值为0.27μM。
IC50: 0.27μM (ACE)
Intravenous injection of Leucylarginylproline (30mg/kg) causes a decrease in the blood pressure. The maximum mean blood pressure reduction (about 15 mmHg) occurrs about 2 min after the injection. Leucylarginylproline peptide reduces the blood pressure by about 15 mmHg at the fourth hour and shows a maximal reduction effect of about 35 mmHg at the eighth hour after oral administration.