| Company Name: |
Alabiochem Tech.Co., Ltd.
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| Tel: |
0512-58900862 400-0707518 |
| Email: |
sales@alabiochem.com |
| Products Intro: |
Product Name:SPDP-PEG12-NHS ester
Purity:>98% HPLC Package:1g;5g;25g;100g;250g;1kg;bulk Remarks:PEG
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| Company Name: |
Xi'an Confluore Biological Technology Co., Ltd.
|
| Tel: |
+86-156-80926068 +86-15680926068 |
| Email: |
1924344760@qq.com |
| Products Intro: |
Product Name:SPDP-PEG12-NHS ester
CAS:2601437-72-1
Purity:99% HPLC Package:10MG;25MG;50MG;100MG;1G;5G Remarks:For customers outside China,please use the website:www.confluore.com
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- SPDP-PEG12-NHS ester
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- $0.00 / 500mg
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2024-03-27
- CAS:2601437-72-1
- Min. Order: 500mg
- Purity: >99.00%
- Supply Ability: 500mg
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| | SPDP-PEG12-NHS ester Basic information |
| Product Name: | SPDP-PEG12-NHS ester | | Synonyms: | SPDP-PEG12-NHS ester;Propanoic acid, 3-[[37-oxo-39-(2-pyridinyldithio)-3,6,9,12,15,18,21,24,27,30,33-undecaoxa-36-azanonatriacont-1-yl]oxy]-, 2,5-dioxo-1-pyrrolidinyl ester | | CAS: | 2601437-72-1 | | MF: | C39H65N3O17S2 | | MW: | 912.07 | | EINECS: | | | Product Categories: | | | Mol File: | 2601437-72-1.mol |  |
| | SPDP-PEG12-NHS ester Chemical Properties |
| density | 1.26±0.1 g/cm3(Predicted) | | pka | 15.01±0.46(Predicted) |
| | SPDP-PEG12-NHS ester Usage And Synthesis |
| Biological Activity | SPDP-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | SPDP-PEG12-NHS ester Preparation Products And Raw materials |
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