1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLIN

1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE Suppliers list
Company Name: Target Molecule Corp
Tel: 781-999-5354
Email: marketing@targetmol.com
Products Intro: Product Name:PK 11195;RP 52028
CAS:85532-75-8
Purity:98.00% Package:5 mg;10 mg;50 mg;100 mg;1 mL * 10 mM (in DMSO) Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Mainchem Co., Ltd.  
Tel: +86-0592-6210733
Email: sale@mainchem.com
Products Intro: Product Name:1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE
CAS:85532-75-8
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833- ;010-82848833-
Email: jkinfo@jkchemical.com;market6@jkchemical.com
Products Intro: Product Name:PK 11195
CAS:85532-75-8
Purity:>98% Package:250Mg,25Mg,50Mg
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801
Email: 3bsc@sina.com
Products Intro: Product Name:PK 11195;1-(2-Chlorophenyl)-N-Methyl-N-(1-Methylpropyl)-3-isoquinolinecarboxaMide
CAS:85532-75-8
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: BOC Sciences  
Tel:
Email: info@bocsci.com
Products Intro: Product Name:PK 11195
CAS:85532-75-8
Purity:98% Remarks:PK 11195 has high affinity for the peripheral benzodiazepine receptor (PBR, TSPO) without binding to other known neurotransmitter receptors. It can also inhibit the human constitutive androstane recep
1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE Basic information
Product Name:1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE
Synonyms:1-(2-chlorophenyl)-n-methyl-n-(1-methylpropyl)-3-isoquinolinecarboxamid;n-methyl-n-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide;1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE;PK 11195;1-(2-chlorophenyl)-N-methyl-*N-(1-methylpropyl)-3;PK 11195 PERIPHERAL BENZODIAZE;1-(2-Chlorophenyl)-N-(1-methylpropyl)-3-isoquinolinecarboxamide;chlorophenylmethyl(1-methylpropyl)isoquinolinecarboxamide
CAS:85532-75-8
MF:C21H21ClN2O
MW:352.86
EINECS:
Product Categories:Miscellaneous Compounds
Mol File:85532-75-8.mol
1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE Structure
1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE Chemical Properties
Boiling point 511.7±45.0 °C(Predicted)
density 1.179±0.06 g/cm3(Predicted)
storage temp. Store at RT
form White crystalline powder.
pka1.76±0.50(Predicted)
CAS DataBase Reference85532-75-8(CAS DataBase Reference)
Safety Information
WGK Germany 3
RTECS NW6987000
MSDS Information
ProviderLanguage
SigmaAldrich English
1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE Usage And Synthesis
UsesPK 11195 is a high affinity peripheral benzodiazepine receptor (PBR) ligand. PK 11195 has been shown to regulate protein phosphorylation in rat brain mitochondria under control of Ca2+. PK11195 promot es mitochondrial apoptosis and blocks P-glycoprotein (Pgp)-mediated drug efflux to chemosensitize cancer cells.
DefinitionChEBI: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Biological ActivityPossesses high affinity for the MDR (peripheral benzodiazepine receptor) without binding to other known neurotransmitter receptors.
1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE Preparation Products And Raw materials
Tag:1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE(85532-75-8) Related Product Information
METHYLPYRIDIN-2-YLMETHYLAMINE DIHYDROCHLORIDE CHEMBRDG-BB 9070750 N-(pyridin-2-ylmethyl)propan-1-amine PYRIDINE-2-CARBOXAMIDE 3-METHYLISOQUINOLINE 6-(4-fluorophenyl)pyridine-2-carbaldehyde 6-METHYL-2-PICOLYL-METHYLAMINE 2-Picolylamine 6-Methyl-2-pyridinemethanamine 2,6-Lutidinehydrochloride 2-METHYL-6-PHENYLPYRIDINE 2-Pyridinecarboxamide,6-methyl-(9CI) (R)-PK11195 CHEMBRDG-BB 9070682 PK11195, [N-METHYL-3H]- Phenylisoquinoline 1-METHYLISOQUINOLINE 1-Tetradecanol