去氢延胡索素
| 中文名称 | 去氢延胡索素 |
|---|---|
| 中文同义词 | 脱氢紫堇碱;去氢延胡索素;脱氢紫堇碱,去氢紫堇碱、去氢延胡索甲素;去氢紫堇碱,去氢延胡索甲素,去氢延胡索素;脱氢紫堇碱(标准品);去氢紫堇碱、去氢延胡索甲素;脱氢紫堇碱(去氢紫堇碱,去氢延胡索甲素,去氢延胡索素);去氢紫堇碱(标准品) |
| 英文名称 | Dehydrocorydaline |
| 英文同义词 | 13-Methylpalmatine;dehydeocorydaline;Dehydrocorydaline;DEHYDROCORYDALINE98%;13-Methyl-2,3,9,10-tetramethoxy-5,6-dihydrodibenzo[a,g]quinolizinium;5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium;Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetramethoxy-13-methyl-;acetate salt of Dehydrocorydaline |
| CAS号 | 30045-16-0 |
| 分子式 | C22H24NO4 |
| 分子量 | 0 |
| EINECS号 | |
| 相关类别 | 中药对照品;标准品;植物提取物;植提标准品;对照品;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;标准品-中药标准品;生物碱;标准品 -中药标准品;分析试剂-对照品;标准品，对照品 |
| Mol文件 | 30045-16-0.mol |
| 结构式 |  |
去氢延胡索素 性质
| 熔点 | 170-173℃ |
|---|---|
| 储存条件 | Inert atmosphere,Room Temperature |
| 溶解度 | 溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。 |
| 形态 | 水晶。 |
| 稳定性 | 吸湿性 |
|
Bcl-2
|
Bax
|
Caspase-7
|
Caspase-8
|
PARP
|
Dehydrocorydaline (0-200 μM) treatment significantly inhibits the growth of MCF-7 cells in a dose-dependent manner. The cell viability is decreased by approximate 40% after 24 h of 200 μM Dehydrocorydaline.
Dehydrocorydaline (0-200 μM)dose-dependently increases Bax protein expression and decreases Bcl-2 protein expression.
Dehydrocorydaline (0-200 μM)induces activation of caspase-7,-8 and the cleavage of PARP without affecting caspase-9.
Dehydrocorydaline manifests a low acute toxicity with an LD 50 of about 277.5±19.0 mg/kg body weight in mice following oral administration and 21.1±1.4 mg/kg for intraperitoneal injection.
药理药效:具有杀菌、消炎作用。
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-N0674 | Dehydrocorydaline | 1 mg | 533元 | |
| 2024/01/25 | HY-N0674 | 去氢延胡索素 Dehydrocorydaline | 30045-16-0 | 5mg | 1400元 |