| Company Name: |
Wuhan ChemFaces Biochemical Co., Ltd.
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18607101326 15172504745 |
| Email: |
aileen@chemfaces.com |
| Products Intro: |
Product Name:Jacoline
CAS:480-76-2
Purity:>=98% Package:5mg ,10mg ,20mg ,50mg ,100mg; 200mg; 500mg or according to customer requirements
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| Company Name: |
Biyu Biotechnology (Shanghai) Co., ltd
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| Tel: |
021-26018599 |
| Email: |
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| Products Intro: |
Product Name:Jacolin
CAS:480-76-2
Purity:>97.0 % Package:10mg,50mg,100mg,500mg,or as request Remarks:BY70139
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| | JACOLINE Basic information |
| Product Name: | JACOLINE | | Synonyms: | JACOLINE;Jacolin;(20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)- | | CAS: | 480-76-2 | | MF: | C18H27NO7 | | MW: | 369.41 | | EINECS: | | | Product Categories: | | | Mol File: | 480-76-2.mol |  |
| | JACOLINE Chemical Properties |
| Melting point | 221°C | | Boiling point | 583.5±50.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | pka | 12.40±0.60(Predicted) |
| | JACOLINE Usage And Synthesis |
| Description | A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D +
48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid,
ClOH1S0 7. The latter contains three hydroxyl and three methyl groups. | | Uses | Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea). | | References | Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959) |
| | JACOLINE Preparation Products And Raw materials |
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