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Z-LEU-LEU-GLU-AMC

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Z-LEU-LEU-GLU-AMC Suppliers list
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 15093356674;
Email: laboratory@coreychem.com
Products Intro: Product Name:Z-Leu-Leu-Glu-AMC
CAS:348086-66-8
Purity:98%; CRYLIU195 Package:1g;0.1USD
Company Name: BOC Sciences
Tel: +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:Z-LLE-AMC
CAS:348086-66-8
Purity:>=95% Remarks:BOC Sciences also provides custom synthesis services for Z-LLE-AMC.
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Products Intro: CAS:348086-66-8
Purity:99% Package:5KG;1KG
Company Name: Nextpeptide Inc
Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Products Intro: Product Name:Z-Leu-Leu-Glu-AMC
CAS:348086-66-8
Purity:98% Min. Package:5KG;1KG
Company Name: Chengdu Youngshe Chemical Co., Ltd.
Tel: +8618108235634
Email: Cecilia@youngshechem.com
Products Intro: Product Name:Z-LLG-AMC
CAS:348086-66-8
Purity:0.98 Package:1G;10G
Z-LEU-LEU-GLU-AMC Basic information
Product Name:Z-LEU-LEU-GLU-AMC
Synonyms:CBZ-LEU-LEU-GLU-AMC;CARBOBENZOXY-L-LEUCYL-L-LEUCYL-L-GLUTAMIC-ACID-ALPHA-(4-METHYLCOUMARINYL)-7-AMIDE;BENZYLOXYCARBONYL-L-LEUCYL-L-LEUCYL-L-GLUTAMIC ACID ALPHA-(4-METHYLCOUMARYL-7-AMIDE);PROTEASOME SUBSTRATE II (FLUOROGENIC);Z-LEU-LEU-GLU-7-AMIDO-4-METHYLCOUMARIN;Z-LEU-LEU-GLU-7-AMINO-4-METHYLCOUMARIN;Z-LEU-LEU-GLU-AMC;Z-LEU-LEU-GLU-MCA
CAS:348086-66-8
MF:C35H44N4O9
MW:664.75
EINECS:
Product Categories:Proteasome substrate II.
Mol File:348086-66-8.mol
Z-LEU-LEU-GLU-AMC Structure
Z-LEU-LEU-GLU-AMC Chemical Properties
Boiling point 967.8±65.0 °C(Predicted)
density 1.253±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble
form solid
pka4.43±0.10(Predicted)
color Solid lyophilized powder
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
Z-LEU-LEU-GLU-AMC Usage And Synthesis
DescriptionZ-LLE-AMC is a fluorogenic substrate for the caspase-like post-glutamate peptide hydrolase of the 26S proteasome or 20S proteolytic core. Caspase-like activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Z-LLE-AMC is typically used in cell lysates after experimental treatment.
UsesA fluorogenic substrate for the peptidylglutamyl-peptide hydrolysing (caspase-like) activity of the proteasome which may be stimulated in the presence of Mg2+ ions and rapidly inactivated by N-acetylimidazole
UsesZ-Leu-Leu-Glu-7-amido-4-methylcoumarin has been used as a fluorogenic substrate for peptidyl glutamyl peptide hydrolase (PGPH) in rat soleus muscle, neonatal cardiomyocytes and rat brain samples.
General DescriptionZ-Leu-Leu-Glu-7-amido-4-methylcoumarin is a fluoropeptide. It acts as a substrate for caspase-like activity.
Biochem/physiol ActionsFluorogenic substrate for the measurement of the peptidylglutamyl-peptide hydrolyzing activity of the 20S proteasome.
storage+4°C
Z-LEU-LEU-GLU-AMC Preparation Products And Raw materials
Tag:Z-LEU-LEU-GLU-AMC(348086-66-8) Related Product Information
Z-LEU-LEU-ARG-AMC Z-LEU-ARG-7-AMINO-4-METHYLCOUMARIN Z-LEU-LEU-OH Z-LLL-AMC BENZYLOXYCARBONYL-L-LEUCYL-L-ARGINYLGLYCYLGLYCINE 4-METHYLCOUMARYL-7-AMIDE H-GLU(AMC)-OH MG-115 Z-LEU-LEU-GLU-AMC Z-LEU-LEU-GLU-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN GLUTAMIC ACID(ANILIDE)-OH