CATHEPSIN G INHIBITOR I

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CAS:429676-93-7
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CAS:429676-93-7
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CAS:429676-93-7
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Products Intro: Product Name:Cathepsin G Inhibitor
CAS:429676-93-7
Purity:95% Package:1mg/RMB 1029.90;5mg/RMB 3604.90
CATHEPSIN G INHIBITOR I Basic information
Product Name:CATHEPSIN G INHIBITOR I
Synonyms:CATHEPSIN G INHIBITOR I;Phosphonic acid, P-[2-[3-[[(1-benzoyl-4-piperidinyl)methylamino]carbonyl]-2-naphthalenyl]-1-(1-naphthalenyl)-2-oxoethyl]-;BOROXIN, TRIS(1-METHYLETHYL);Cathepsin G Inhibitor, cathepsin G inhibitor
CAS:429676-93-7
MF:C36H33N2O6P
MW:620.64
EINECS:
Product Categories:A potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G.
Mol File:429676-93-7.mol
CATHEPSIN G INHIBITOR I Structure
CATHEPSIN G INHIBITOR I Chemical Properties
Boiling point 912.0±75.0 °C(Predicted)
density 1.40±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka1.51±0.10(Predicted)
form Solid
color White to off-white
Sensitive Light Sensitive
Safety Information
MSDS Information
CATHEPSIN G INHIBITOR I Usage And Synthesis
DescriptionCathepsin G inhibitor I is a potent and selective inhibitor of cathepsin G (IC50 = 53 nM). It weakly inhibits or has no effect on related proteases, including chymotrypsin, thrombin, plasmin, trypsin, tryptase, and elastase.
UsesCathepsin G inhibitor I is a potent and selective inhibitor of cathepsin G.
targetcathepsins G
references[1] greco mn, hawkins mj, powell et, almond hr jr, corcoran tw, de garavilla l, kauffman ja, recacha r, chattopadhyay d, andrade-gordon p, maryanoff be. nonpeptide inhibitors of cathepsin g: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design. j am chem soc. 2002;124(15):3810-1.
CATHEPSIN G INHIBITOR I Preparation Products And Raw materials
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