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BOC Sciences
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1-631-485-4226; 16314854226 |
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info@bocsci.com |
| Products Intro: |
Product Name:OPC-28326
CAS:167626-17-7
Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 13348960310 |
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3003867561@qq.com |
| Products Intro: |
Product Name:OPC-28326
CAS:167626-17-7
Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg
|
OPC-28326 manufacturers
- OPC-28326
-
- $197.00
-
2026-05-11
- CAS:167626-17-7
- Purity: 99.79%
- Supply Ability: 10g
- OPC-28326
-
- $197.00
-
2026-05-11
- CAS:167626-17-7
- Purity: 99.79%
- Supply Ability: 10g
|
| | OPC-28326 Basic information |
| Product Name: | OPC-28326 | | Synonyms: | OPC-28326;OPC28326,OPC 28326;Propanamide, N-[2,6-dimethyl-4-[[4-[methyl(2-phenylethyl)amino]-1-piperidinyl]carbonyl]phenyl]-;OPC-28326, 10 mM in DMSO | | CAS: | 167626-17-7 | | MF: | C26H35N3O2 | | MW: | 421.58 | | EINECS: | | | Product Categories: | | | Mol File: | 167626-17-7.mol |  |
| | OPC-28326 Chemical Properties |
| Boiling point | 624.5±55.0 °C(Predicted) | | density | 1.13±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 14.79±0.70(Predicted) |
| | OPC-28326 Usage And Synthesis |
| Uses | OPC-28326 is a selective peripheral vasodilator and an angatonist of α2-adrenergic receptor, with Ki of 2040, 285, and 55 nM for α2A-, α2B- and α2C-adrenoceptors, respectively. | | in vivo | OPC-28326 augments blood flow recovery in murine hindlimb ischemia. OPC-28326 significantly increases the number of histologically detectable capillaries in the ischemic leg. OPC-28326 has no beneficial effects on blood flow recovery in eNOS / mice[1]. OPC-28326 (3-30 mg/kg, i.v.) and yohimbine causes dose-dependent rightward shift in the pressor dose-response curve induced by B-HT 920. OPC-28326 does not affect on the mydriasis in rats[2]. | | IC 50 | α adrenergic receptor | | References | [1] Sumi M, et al. OPC-28326, a selective femoral arterial vasodilator, augments ischemia induced angiogenesis. Biomed Pharmacother. 2007 May;61(4):209-15. Epub 2006 Dec 28. DOI:10.1016/j.biopha.2006.12.004
[2] Orito K, et al. alpha(2)-adrenoceptor antagonist properties of OPC-28326, a novel selective peripheral vasodilator. Br J Pharmacol. 2001 Oct;134(4):763-70. DOI:10.1038/sj.bjp.0704309 |
| | OPC-28326 Preparation Products And Raw materials |
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