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| | LITHIUM TETRAMETHYLPIPERIDIDE Basic information |
| Product Name: | LITHIUM TETRAMETHYLPIPERIDIDE | | Synonyms: | LITHIUM TETRAMETHYLPIPERIDIDE;Lithium·2,2,6,6-tetramethylpiperidine;LithiuM 2,2,6,6-tetraMethylpiperidide 97%;2,2,6,6-Tetramethylpiperidine lithium salt (1:1);Piperidine,2,2,6,6-tetramethyl-, lithium salt (1:1);ithium 2,2,6,6-tetramethyL;"2,2,6,6-tetramethylpiperidine lithium";Piperidine, 2,2,6,6-tetramethyl-, lithium salt | | CAS: | 38227-87-1 | | MF: | C9H20LiN | | MW: | 149.21 | | EINECS: | 684-475-5 | | Product Categories: | | | Mol File: | 38227-87-1.mol |  |
| | LITHIUM TETRAMETHYLPIPERIDIDE Chemical Properties |
| | LITHIUM TETRAMETHYLPIPERIDIDE Usage And Synthesis |
| Uses | Lithium 2,2,6,6-tetramethylpiperidide is a strong base and can be used:
- For the synthesis of enamines from terminal epoxides through trans-α-lithiated epoxide as an intermediate.
- For ortholithiation of arenes such as 1,3-bis(trifluoromethyl)benzene, 4,4-dimethyl-2-phenyl-2-oxazoline, 1,4-bis(trifluoromethyl)benzene and 1,3-dimethoxybenzene.
- In combination with Lewis donor ligand, N,N,N′,N′-tetramethylethylenediamine (TMEDA) for deprotonative metalation of methoxy-substituted arenes.{21]
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| | LITHIUM TETRAMETHYLPIPERIDIDE Preparation Products And Raw materials |
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