N-Mal-N-bis(PEG4-NH-Boc) manufacturers
- N-Mal-N-bis(PEG4-NH-Boc)
-
- $0.00 / 500mg
-
2025-06-07
- CAS:2128735-27-1
- Min. Order: 500mg
- Purity: >95.00%
- Supply Ability: 500mg
|
| | N-Mal-N-bis(PEG4-NH-Boc) Basic information |
| Product Name: | N-Mal-N-bis(PEG4-NH-Boc) | | Synonyms: | N-Mal-N-bis(PEG4-NH-Boc);5,8,11,14,20,23,26,29-Octaoxa-2,17,32-triazatritriacontanedioic acid, 17-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-, 1,33-bis(1,1-dimethylethyl) ester | | CAS: | 2128735-27-1 | | MF: | C37H66N4O15 | | MW: | 806.94 | | EINECS: | | | Product Categories: | | | Mol File: | 2128735-27-1.mol |  |
| | N-Mal-N-bis(PEG4-NH-Boc) Chemical Properties |
| Boiling point | 839.2±65.0 °C(Predicted) | | density | 1.160±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | solubility | Soluble in DMSO, DCM, DMF | | pka | 11.92±0.46(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | N-Mal-N-bis(PEG4-NH-Boc) Usage And Synthesis |
| Description | N-Mal-N-bis(PEG4-NH-Boc) is an maleimide linker. It can react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. Boc protected amines can be deprotected under acidic conditions. | | Uses | N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N-Mal-N-bis(PEG4-NH-Boc) Preparation Products And Raw materials |
|