- 2-Deoxy-L-ribose
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- $60.00 / 1kg
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2023-08-16
- CAS:18546-37-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000tons
- 2-Deoxy-L-ribose
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- $100.00 / 25kg
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2023-01-31
- CAS:18546-37-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 50000KG/month
- 2-Deoxy-L-ribose
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- $0.00 / 1kg
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2022-09-30
- CAS:18546-37-7
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
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| | 2-Deoxy-L-ribose Basic information |
| | 2-Deoxy-L-ribose Chemical Properties |
| Melting point | 69-72°C | | alpha | 57 º (c=0.9 H2O after 24h) | | Boiling point | 167.23°C (rough estimate) | | density | 1.0590 (rough estimate) | | refractive index | 1.4050 (estimate) | | storage temp. | Inert atmosphere,2-8°C | | solubility | Methanol (Slightly), Water (Slightly) | | pka | 13.58±0.20(Predicted) | | form | Solid | | color | Light Yellow to Pale Beige | | optical activity | [α]/D 54.0±2.0°, 24 hr, c = 1 in H2O | | CAS DataBase Reference | 18546-37-7(CAS DataBase Reference) |
| Provider | Language |
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ACROS
| English |
| | 2-Deoxy-L-ribose Usage And Synthesis |
| Chemical Properties | white to light beige crystalline powder | | Uses | 2-Deoxy-L-ribose is an isomer of 2-Deoxy-D-ribose (D252000) which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. | | Definition | ChEBI: 2-deoxy-L-arabinose is a deoxypentose. It is functionally related to a L-arabinose. | | Production Methods | The provides the synthetic process of 2-Deoxy-L-ribose comprising the steps of; (A) protection step in which aldehyde group of 2-deoxy-D-ribose is protected in the form of acetal. 2-deoxy-l-O-alkyl-D-ribopyranoside is prepared by the reaction of 2-deoxy-D-ribose with alcohol in the presence of acid; (B) activation step in which 3 -and 4-OH groups of 2-deoxy-D-ribose are activated. 2-deoxy-l-O-alkyl- 3,4-di-(alkanesulfonyl)-D-ribose or 2-deoxy-1-O-alkyl-3,4-di-(arylsulfonyl)-D-ribose is prepared by reaction of the above 2-deoxy-l-O-alkyl-D-ribose with organic sulfonylhalide for activation of 3- and 4-OH; (C) inversion step in which stereochemistry of 3- and 4-OH groups is changed. Reaction of the above 2-deoxy-l- O-alkyl-3,4-di-(alkanesulfonyl)-D-ribose or 2-deoxy-l-O-alkyl-3,4-di-(arylsulfonyl)- D-ribose with a metal salt of organic acid leads to 2-deoxy-L-ribose derivatives of which stereochemistry of 3- and 4-OH is different from the corresponding 2-deoxy-D- ribose derivatives; (D) deprotection step in which 2-deoxy-L-ribose is prepared by consecutive reactions of the step (C) products with acid and base. | | Purification Methods | Crystallise 2-deoxy--L-ribose from diethyl ether. It can also be purified by dissolving the ribose (7.3g) in EtOAc (3L) by reflux, decanting from any insoluble mate |
| | 2-Deoxy-L-ribose Preparation Products And Raw materials |
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