人体胰脏多肽
| 中文名称 | 人体胰脏多肽 |
|---|---|
| 中文同义词 | 人体胰脏多肽;人体胰脏多肽, ≥95% (HPLC);人胰腺多肽;人胰多肽 (HPP);小鼠胰多肽ELISA试剂盒;胰腺多肽PANCREATICPOLY PEPTIDE , HUMAN |
| 英文名称 | PANCREATIC POLYPEPTIDE, HUMAN |
| 英文同义词 | M.W. 4181.71 C185H287N53O54S2;H-ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2;APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY-NH2;ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2;ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2;ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2 HUMAN;PP, HUMAN;PANCREATIC POLYPEPTIDE |
| CAS号 | 75976-10-2 |
| 分子式 | C185H287N53O54S2 |
| 分子量 | 4181.71098 |
| EINECS号 | |
| 相关类别 | 生化试剂;其他生化试剂;标准品;Peptide;Neuropeptide Y (NPY ) receptor |
| Mol文件 | 75976-10-2.mol |
| 结构式 |  |
人体胰脏多肽 性质
| 储存条件 | -15°C |
|---|---|
| 溶解度 | 水：1mg/mL |
| 形态 | 粉末 |
| 水溶解性 | Soluble to 0.70 mg/ml in water |
Neuropeptide Y (NPY) Y4/Y5 receptor
Human pancreatic polypeptide (hPP) is one such peptide, being released postprandially from F cells of the pancreatic islets depending on caloric load, food consumption and circadian rhythm. It is a C-terminally amidated 36 amino acid peptide with a characteristic hairpin-like pancreatic polypeptide (PP)-fold and acts at the Y4 receptor to induce satiety and delay gastric emptying and motility. Addition of the human pancreatic polypeptide (hPP) (10 nM-1 μM) results in a significant, dose-dependent reduction in both basal and stimulated release. Human pancreatic polypeptide (hPP) can also inhibit basal and stimulated NPY release with a pharmacological profile suggesting a role for Y4 presynaptic receptors.