| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:Adimolol
CAS:75708-29-1
Purity:NULL Package:10mg;25mg;50mg;5mg Remarks:NULL
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:MEN935;MEN935
CAS:75708-29-1
Purity:98% Package:5 mg
|
|
| | MEN 935 Basic information |
| Product Name: | MEN 935 | | Synonyms: | MEN 935;3-[3-[(2-hydroxy-3-naphthalen-1-yloxypropyl)amino]-3-methylbutyl]-1H-benzimidazol-2-one | | CAS: | 75708-29-1 | | MF: | C25H29N3O3.ClH.H2O | | MW: | 473.998 | | EINECS: | | | Product Categories: | | | Mol File: | 75708-29-1.mol |  |
| | MEN 935 Chemical Properties |
| | MEN 935 Usage And Synthesis |
| Originator | Adimolol
hydrochloride
,ZYF Pharm
Chemical | | Uses | Adimolol is an antihypertensive agent and a β-adrenoceptor blocker. | | Manufacturing Process | A mixture consisting of 3 g of 1-(3-amino-3,3-dimethyl-n-propyl)
benzimidazolidinone-2, 3.3 g of 1-[naphthyl-(1)-oxyl]propylene-(2,3)-epoxide
and 12 ml of 98% ethanol were refluxed for three hours. Thereafter, the
ethanol was distilled off, the residue was taken up in some methanol, and the
solution was acidified with 1 N hydrochloric acid and then extracted with ethyl
acetate. The ethyl acetate was distilled out of the extract solution, and ether
and some water were added to the residue, whereupon a crystalline substance
separated out. The product was recrystallized from ethanol, yielding 60% of
theory of ()-1-(3-((2-hydroxy-3-(1-naphthyloxy)propyl)amino)-3-
methylbutyl)-2-benzimidazolinone, which had a melting point of 161°C.
In practice it is usually used as hydrochloride. | | Therapeutic Function | Alpa- and Beta-adrenergic blocker |
| | MEN 935 Preparation Products And Raw materials |
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