| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:CGP 12177 hydrochloride;4-[3-[(1,1-DiMethylethyl)aMino]2-hydroxypropoxy]-1,3-dihydro-2H-benziMidazol-2-onehydrochloride
CAS:81047-99-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:CGP 12177
CAS:81047-99-6
Purity:98% Remarks:CGP 12177 is a partial β3-adrenoceptor agonist with Ki value of 88 nM. It is also an of β1- and β2-adrenoceptors antagonist with Ki values of 0.9 nM and 4 nM for β1-, β2adrenoceptors. CGP12177 can sli
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| Company Name: |
HBCChem, Inc.
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| Tel: |
+1-510-219-6317 |
| Email: |
sales@hbcchem.com |
| Products Intro: |
Product Name:4-(3-tert-ButylaMino-2-Hydroxypropoxy)benziMidazol-2-One
CAS:81047-99-6
Purity:99.46% Package:100g; 500g; 1kg Remarks:HBC0491
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| | (+/-)-CGP-12177 HYDROCHLORIDE Basic information |
| Product Name: | (+/-)-CGP-12177 HYDROCHLORIDE | | Synonyms: | (+/-)-CGP-12177 HYDROCHLORIDE;CGP 12177 HYDROCHLORIDE;4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE HYDROCHLORIDE;CGP12177HCl;CGP 12177 hydochloride;CGP 12177;4-(3-tert-Butylamino-2-Hydroxypropoxy)benzimidazol-2-One;4-(3-tert-Butylamino-2-hydroxypropoxy)-1H-benzimidazol-2(3H)-one | | CAS: | 81047-99-6 | | MF: | C14H21N3O3 | | MW: | 279.33 | | EINECS: | | | Product Categories: | Adrenoceptor | | Mol File: | 81047-99-6.mol |  |
| | (+/-)-CGP-12177 HYDROCHLORIDE Chemical Properties |
| Melting point | >256°C (dec.) | | Boiling point | 376.3±37.0 °C(Predicted) | | density | 1.179 | | storage temp. | Store at RT | | solubility | DMSO: >10 mg/mL | | pka | 11.48±0.30(Predicted) | | form | solid | | color | white |
| | (+/-)-CGP-12177 HYDROCHLORIDE Usage And Synthesis |
| Uses | CGP 12177 Hydrochloride is a selective β3-adrenoceptor agonist. | | Definition | ChEBI: A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group. | | Biological Activity | Partial agonist at β 3 -adrenoceptors. β 1 - and β 2 -adrenoceptor antagonist (K i values are 0.9, 4 and 88 nM for β 1 , β 2 and β 3 receptors respectively). |
| | (+/-)-CGP-12177 HYDROCHLORIDE Preparation Products And Raw materials |
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