异七叶皂苷 IB
中文名称 | 异七叶皂苷 IB |
---|---|
中文同义词 | 异七叶皂苷 IB;七叶皂苷D(异七叶皂苷IB);异七叶树皂苷IB |
英文名称 | Isoescin IB |
英文同义词 | Aescin D;Escin IVb;Isoescin Ib;Isoescin IB(Isoaescin IB);(3beta,4beta,16alpha,21beta,22alpha)-28-(Acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-beta-D-glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-4)]-beta-D-glucopyranosiduronic acid;Escin Impurity 4(Isoescin IB);β-D-Glucopyranosiduronic acid, (3β,4β,16α,21β,22α)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-;Escin,inhibit,Inhibitor,Escin IB,Isoescin IB |
CAS号 | 219944-46-4 |
分子式 | C55H86O24 |
分子量 | 1131.26 |
EINECS号 | |
相关类别 | 植物提取物;标准品;对照品;中药对照品;标准品-中药标准品;三萜;标准品 -中药标准品;标准品,对照品 |
Mol文件 | 219944-46-4.mol |
结构式 |
异七叶皂苷 IB 性质
沸点 | 1148.1±65.0 °C(Predicted) |
---|---|
密度 | 1.46 |
溶解度 | 溶于甲醇; |
酸度系数(pKa) | 2.63±0.70(Predicted) |
形态 | 粉末 |
颜色 | 白色 |
水溶解性 | slightly soluble in water |
β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts. β-escin can inhibit proliferation and/or induce apoptosis in various types of cancer cells including A549 cell, HT-29 cell, HCC cell, OVCAR3 cell and H-Ras 5RP7 cell. β-escin may be useful as a chemopreventive agent, especially for tumors associated with an inflammatory response.
As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024/01/25 | HY-N0557 | Isoescin IB | 1 mg | 660元 | |
2024/01/25 | HY-N0557 | 异七叶皂苷 IB Isoescin IB | 219944-46-4 | 5mg | 1650元 |