108226-05-7
| 中文名称 | 108226-05-7 |
|---|---|
| 中文同义词 | 化合物 T13570 |
| 英文名称 | Benzamide, 4-amino-5-chloro-2-propoxy-N-[1-[3-(tetrahydro-2-furanyl)propyl]-4-piperidinyl]- |
| 英文同义词 | Benzamide, 4-amino-5-chloro-2-propoxy-N-[1-[3-(tetrahydro-2-furanyl)propyl]-4-piperidinyl]-;BENZAMIDE DERIVATIVE 1 |
| CAS号 | 108226-05-7 |
| 分子式 | C22H34ClN3O3 |
| 分子量 | 423.97666 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 108226-05-7.mol |
| 结构式 |  |
108226-05-7 性质
| 沸点 | 556.4±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.20±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 13.65±0.20(Predicted) |
Benzamide Derivative 1 是来自专利 EP0213775A1，化合物 18，的苯甲酰胺衍生物。Benzamide Derivative 1 有潜力用于胃肠疾病的研究。
Dopamine, mACh receptor
Substituted benzamides have been shown to possess a number of pharmacological properties most of which are related to their ability to antagonize the central and peripheral effects of dopamine and/or facilitate the release of acetylcholine on to muscarinic receptors in the gastrointestinal smooth muscle. This has led to their successful clinical use as antiemetic and in the treatment of a wide range of gastrointestinal disorders of somatic, psychosomatic and iatrogenic origin.