ChemicalBook > Product Catalog >API >Nervous system drugs >Other nervous system drugs >BARBITAL


BARBITAL Basic information
Product Name:BARBITAL
Synonyms:barbital free acid crystalline--dea*schedule iv I;barbital methanol solution;Barbital(barbitone);BARBITAL FREE ACID CRYSTALLINE--DEASCHED ULE IV ITE;BARBITAL, FOR ANALYTICAL PURPOSE (EXPORT CONTROL);BarbitonePh.Eur.+++;BARBITAL 99% GR;BARBITAL,POWDER,PURIFIED
Product Categories:RECI;Pyrimidines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:57-44-3.mol
BARBITAL Structure
BARBITAL Chemical Properties
Melting point 188-192°C
Boiling point 318.14°C (rough estimate)
density 1.2200
refractive index 1.4200 (estimate)
Fp 11 °C
storage temp. 2-8°C
pka7.43(at 25℃)
color Faintly bitter crystals from H2O; polymorphicforms; triagonal crystals, monoclinic prisms, monoclinicneedles, and triclinic cryst
Water Solubility 7.149g/L(25 ºC)
Merck 13,965
EPA Substance Registry System5,5-Diethylbarbituric acid (57-44-3)
Safety Information
Hazard Codes Xn,T,F
Risk Statements 22-39/23/24/25-23/24/25-11-63-40-20
Safety Statements 36-45-36/37-16-7
RIDADR UN 1230 3/PG 2
WGK Germany 3
RTECS CQ3500000
ToxicityLDLo orl-cat: 280 mg/kg PHREA7 19,472,39
MSDS Information
SigmaAldrich English
BARBITAL Usage And Synthesis
Chemical PropertiesWhite crystals or powder; bitter taste; odorless. Stable in air. Soluble in hot water, alcohol, ether, acetone, and ethyl acetate.
UsesPrototype of the barbiturate hypnotics.
DefinitionChEBI: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by two ethyl groups. Formerly used as a hypnotic (sleeping aid).
Brand nameDormileno;Escoderm;Hypnogene;Hypnox;Lidor;Megal;Plexonal;Somnytic tablets;Verinogen;Verodon;Veroletten;Verolitten;Veronigen.
World Health Organization (WHO)Barbital is a long-acting barbiturate which is controlled under Schedule IV of the 1971 Convention on Psychotropic Substances. See WHO comment for barbiturates. (Reference: (UNCPS4) United Nations Convention on Psychotropic Substances (IV), , , 1971)
Safety ProfilePoison by ingestion, intravenous,intraperitoneal, and subcutaneous routes. Ingestion causespsychological effects in humans. Mutation data reported.When heated to decomposition it emits toxic fumes ofNOx. An hypnotic andsedative.
Purification MethodsCrystallise barbital from water or EtOH and dry it in a vacuum over P2O5. [Beilstein 24 III/IV 1901.]
BARBITAL Preparation Products And Raw materials
Tag:BARBITAL(57-44-3) Related Product Information
BARBITAL-D5 (ETHYL-D5) HEXOBARBITAL Sodium Phenol Barbital Barbital-acetamide(1:1) barbital N-glucoside Gelatin Barbital Buffer, GVB2+ BARBITAL BUFFER CONCENTRATE, PGE WITH 12 FLASKS* Barbital (base and/or unspecified salts) BARBITAL BUFFER,Barbital buffer concentrate,Barbital buffer solution, Buffer concentrate from sodium barbital and barbital, Sodium barbital buffer solution 1,3-Dimethylbarbituric acid METHOHEXITAL-D5 Probarbital 5,5-BIS[2-(4-METHOXYPHENYL)-2-OXOETHYL]-1,3-DIMETHYL-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE BARBITAL 5-ISOBUTYL-5-(2-TETRAHYDROPYRANYL)BARBITURIC ACID 1,3-dimethylbarbital METHARBITAL CIII (200 MG) Pentobarbital