5-HYDROXY-2'-DEOXYURIDINE
中文名称 | 5-HYDROXY-2'-DEOXYURIDINE |
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中文同义词 | 5-羟基-2'-脱氧尿苷;化合物 T19152;2'-脱氧-5-羟基尿苷 |
英文名称 | 5-HYDROXY-2'-DEOXYURIDINE |
英文同义词 | 5-HYDROXY-2'-DEOXYURIDINE;Oh-5-du;Uridine, 2'-deoxy-5-hydroxy-;2'-Deoxy-5-hydroxyuridine;2'-DEOXY-5-HYDROXY-D-URIDINE;5-OHdU |
CAS号 | 5168-36-5 |
分子式 | C9H12N2O6 |
分子量 | 244.2 |
EINECS号 | |
相关类别 | |
Mol文件 | 5168-36-5.mol |
结构式 |
5-HYDROXY-2'-DEOXYURIDINE 性质
储存条件 | Hygroscopic, -20°C Freezer, Under inert atmosphere |
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溶解度 | 加热、超声处理轻微溶于甲醇、轻微溶于水 |
形态 | 固体 |
颜色 | 白色至类白色 |
水溶解性 | Water: 10 mg/mL (40.95 mM) |
稳定性 | 吸湿性 |
Human Endogenous Metabolite
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To study the specificity of nucleotide incorporation opposite 5-hydroxypyrimidines in template DNA, 18- and 45-member oligodeoxyribonucleotides, containing an internal 2'-deoxy-5-hydroxyuridine (5-OHdU) in two different sequence contexts, were used. Translesion synthesis past 2'-deoxy-5-hydroxyuridine (5-OHdU) in both oligonucleotides occurred, but pauses both opposite, and one nucleotide prior to, the modified base in the template is observed. The specificity of nucleotide incorporation opposite 2'-deoxy-5-hydroxyuridine (5-OHdU) in the template is sequence context dependent. In one sequence context, dA is the principal nucleotide incorporated opposite 2'-deoxy-5-hydroxyuridine (5-OHdU). However in a second sequence context, dC is the predominant base incorporated opposite 2'-deoxy-5-hydroxyuridine (5-OHdU). In that same sequence context, dC is also the predominant nucleotide incorporated opposite 2'-deoxy-5-hydroxyuridine (5-OHdU).
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/04/30 | HY-130801 | 5-Hydroxy-2'-deoxyuridine | 5 mg | 900元 | |
2024/04/30 | HY-130801 | 5-HYDROXY-2'-DEOXYURIDINE 5-Hydroxy-2'-deoxyuridine | 5168-36-5 | 10 mM * 1 mLin DMSO | 990元 |