- 4-Bromoisoquinoline
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- $100.00 / 1KG
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2023-12-24
- CAS:1532-97-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 4-Bromoisoquinoline
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- $30.00 / 1kg
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2023-04-13
- CAS:1532-97-4
- Min. Order: 10kg
- Purity: 99%
- Supply Ability: 100000kg
- 4-Bromoisoquinoline
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- $0.00 / 25KG
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2023-01-31
- CAS:1532-97-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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| | 4-Bromoisoquinoline Basic information |
| | 4-Bromoisoquinoline Chemical Properties |
| Melting point | 40-43 °C (lit.) | | Boiling point | 280-285 °C (lit.) | | density | 1.5617 (rough estimate) | | refractive index | 1.6641 (estimate) | | Fp | >230 °F | | storage temp. | 2-8°C | | solubility | Chloroform, Methanol | | pka | 3.30±0.10(Predicted) | | form | Crystalline Solid | | color | White to light beige | | BRN | 114431 | | InChI | InChI=1S/C9H6BrN/c10-9-6-11-5-7-3-1-2-4-8(7)9/h1-6H | | InChIKey | SCRBSGZBTHKAHU-UHFFFAOYSA-N | | SMILES | C1C2=C(C=CC=C2)C(Br)=CN=1 | | CAS DataBase Reference | 1532-97-4(CAS DataBase Reference) | | NIST Chemistry Reference | Isoquinoline, 4-bromo-(1532-97-4) |
| | 4-Bromoisoquinoline Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid | | Uses | Shows selective inhibition of cAMP-dependent protein kinase | | Preparation | 2-Alkynyl benzyl azides could smoothly undergo an electrocyclic reaction catalyzed by palladium to afford either 4-bromoisoquinoline or 4-bromoisquinolones selectively under different conditions. 4-Bromoisoquinoline was synthesised in the presence of PdBr2/CuBr2/LiBr in MeCN, and 4-bromoisoquinolone was selectively produced with PdBr2/CuBr2/HOAc in CH2ClCH2Cl[1].
| | Synthesis Reference(s) | Journal of Heterocyclic Chemistry, 10, p. 409, 1973 DOI: 10.1002/jhet.5570100326 | | References |
[1] Hong-ping Zhang, Hongzhan Xiao, Hong‐Yan Li. “A Selective Synthesis of 4-Bromoisoquinoline and 4-Bromoisquinolone.” Journal of Chemical Research-s (2013).
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| | 4-Bromoisoquinoline Preparation Products And Raw materials |
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