| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:Anti-glutaMate transporter GLT-1
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Atlas antibodies
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| Tel: |
46-854595850 |
| Email: |
order@atlasantibodies.com |
| Products Intro: |
Product Name:Anti-SLC1A2
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Anti-SIGLEC5 antibody produced in rabbit
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| Company Name: |
Neobioscience Co., Ltd.
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| Tel: |
4006-800-892 |
| Email: |
info@neobioscience.com |
| Products Intro: |
Product Name:Anti-SLC1A2
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| | ANTI-EAAT2 Basic information |
| Product Name: | ANTI-EAAT2 | | Synonyms: | Anti-SLC1A1 antibody produced in rabbit;Anti-SLC1A1, (N-terminal) antibody produced in rabbit;Anti-EAAT2 antibody produced in rabbit;Anti-SIGLEC5 antibody produced in rabbit;Anti-SLC1A3 antibody produced in rabbit;Anti-SLC1A1 (C-terminal) antibody produced in rabbit;Anti-EAAC1 antibody produced in rabbit;ANTI-GLUTAMATE TRANSPORTER EAAC1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-EAAT2 Structure]() |
| | ANTI-EAAT2 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| | ANTI-EAAT2 Usage And Synthesis |
| Biological Activity | SIGLEC5 (sialic acid binding Ig like lectin 5) is involved in immunosppressiveness by interacting in a hemophilic manner. It interacts with acute phase protein a1-acid glycoprotein, group B streptococcal cell-wall-anchored β protein and the sialylated lipopolysaccharide of Neisseria meningitides. This protein recruits the phosphatases SHP-1 and SHP-2 to its intracellular ITIMs (immunoreceptor tyrosine-based inhibitory motif), which prevents the activation of kinase-dependent activation cascades. Unmasking of this protein is essential for the proinflammatory effect of S. pneumoniae desialylation of the leukocyte cell surface. Interaction of Group B Streptococcus (GBS) β protein with SIGLEC5 results in suppression of human leukocytes phagocytosis function, oxidative burst, and extracellular trap production. This leads to increased bacterial survival. |
| | ANTI-EAAT2 Preparation Products And Raw materials |
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