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ChemicalBook Optimization Suppliers |
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| 融点 | -1 °C | | 沸点 | 248 °C(lit.) | | 比重(密度) | 1.121 | | 蒸気密度 | 4.7 (vs air) | | 蒸気圧 | <1 hPa (20 °C) | | FEMA | 2670 | P-METHOXYBENZALDEHYDE | | 屈折率 | n20/D 1.573(lit.) | | 闪点 | 228 °F | | 貯蔵温度 | Store below +30°C. | | 溶解性 | 2g/l | | 外見 | Liquid | | 色 | Clear colorless to yellow | | PH | 7 (2g/l, H2O, 20℃) | | 臭い (Odor) | sweetish odor | | 爆発限界(explosive limit) | 1.4-5.3%(V) | | においのタイプ | anisic | | 水溶解度 | Miscible with acetone, alcohol, ether, chloroform and benzene. Immiscible with water. | | Sensitive | Air Sensitive | | Decomposition | > 160°C | | Merck | 14,663 | | JECFA Number | 878 | | BRN | 471382 | | Dielectric constant | 15.8（20℃） | | InChIKey | ZRSNZINYAWTAHE-UHFFFAOYSA-N | | LogP | 1.56 at 25℃ | | CAS データベース | 123-11-5(CAS DataBase Reference) | | NISTの化学物質情報 | Benzaldehyde, 4-methoxy-(123-11-5) | | EPAの化学物質情報 | Benzaldehyde, 4-methoxy- (123-11-5) |
| | p-アニスアルデヒド Usage And Synthesis |
| 外観 | 無色～うすい黄褐色, 澄明の液体 | | 定義 | 本品は、次の化学式で表される有機化合物である。 | | 溶解性 | 水に微溶。エタノール, アセトンに易溶。エタノール及びアセトンに極めて溶けやすく、水に溶けにくい。 | | 解説 |
P-アニスアルデヒド液体,沸点248 ℃．d2041.1143，d1515 1.127～1.130．n20D 1.5713．有機溶媒に可溶，水に微溶．特有の香りをもち，スイートピーなどの花精油の調合用，せっけん用の香料，医薬品の合成原料に用いられる．
森北出版「化学辞典（第2版）
| | 用途 | 花精油(スイートピー、ホーソン、アカシア、ミモサ、ライラック)香料。 セッケン香料として用いられる。 | | 用途 | 香料、トイレ用石鹸 | | 製造 | p-アニスアルデヒド,アニス油，ういきょう油などのなかに存在するが，p-メトキシトルエンを二酸化マンガンその他で酸化して合成される． | | 化粧品の成分用途 | 香料 | | 使用上の注意 | アルゴン封入 | | 説明 | p-Methoxybenzaldehyde has a characteristic hawthorne odor and
a pungent, anise-like flavor. It has a bitter flavor above 30 - 40 ppm.
May be prepared by methylation and oxidation of p-cresol and
also by oxidation of anethole. | | 化学的特性 | p-Anisaldehyde is a colorless to slightly yellowish liquid with a sweet, mimosa, hawthorn odor. It occurs in many essential oils, often together with anethole. It can be hydrogenated to anise alcohol and readily oxidizes to anisic acid when exposed to air. It is miscible in alcohol, ether, and most fixed oils, soluble in propylene glycol, insoluble in glycerin, water, and mineral oil. | | 天然物の起源 | Reported found in essential oils and extracts of vanilla, Acacia farmesiana Willd., Magnoila salicifolia
Maxim., Erica arborea, Pirus communis, Boswellia serrata, and others; also in anise, fennel and star anise (especially when aged
due to the oxidation of anethole), cranberry, black currant, cinnamon and basil. | | 使用 | 4-Methoxybenzaldehyde is widely utilized in the fragrance and flavor industry. It finds application as an important intermediate in the synthesis of other organic compounds, perfumes and pharmaceuticals like antihistamines. It is also used in the preparation of agrochemicals, dyes and plastic additives. A solution of para-anisaldehyde with acid and ethanol is used as stain in thin layer chromatography (TLC), which provides easy identification of different compounds. | | 使用 | Perfumery and toilet soaps; odor resembles that of coumarin, but the aldehyde must be mixed with other odorous substances to yield an agreeable odor. Also used in organic syntheses. | | 定義 | ChEBI: P-methoxybenzaldehyde is a member of the class of benzaldehydes consisting of benzaldehyde itself carrying a methoxy substituent at position 4. It has a role as an insect repellent, a human urinary metabolite, a plant metabolite and a bacterial metabolite. | | 製造方法 | By methylation and oxidation of p-cresol and also by oxidation of anethole. | | Aroma threshold values | Aroma characteristics at 1.0%: sweet powdery, spicy creamy, fruity, vanilla and hay-like. Coumarin,
almond, anisic with berry nuances. | | Taste threshold values | Taste characteristics at 5 to 10 ppm: sweet powdery, vanilla creamy, spice anise, nutty, cherry pit and
almond-like nuances. | | Synthesis Reference(s) | Chemical and Pharmaceutical Bulletin, 42, p. 1041, 1994 DOI: 10.1248/cpb.42.1041
Tetrahedron Letters, 43, p. 1395, 2002 DOI: 10.1016/S0040-4039(02)00027-8 | | 一般的な説明 | p-anisaldehyde is an aromatic aldehyde commonly found in anise seed oil. It shows acaricidal activity and is primarily used, as a lead compound for the development of new agents for the selective control of house dust mites. | | 燃焼性と爆発性 | Non flammable | | Biochem/physiol Actions | Taste at 5-10 ppm | | 安全性プロファイル | Moderately toxic by
ingestion. A skin irritant. Mutation data
reported. Combustible liquid. When heated
to decomposition it emits acrid smoke and
irritating fumes | | target | Antifection | | 代謝 | Anisic aldehyde undergoes a very slight degree of demethylation with oxidation of its aldehyde group to an acid group, the major metabolite excreted being anisic
acid (Williams, 1959). | | 純化方法 | Wash the aldehyde with saturated aqueous NaHCO3, then H2O, steam distil, extract the distillate with Et2O, dry (MgSO4) the extract, filter and distil this under a vacuum and N2. Store it in glass ampules under N2 in the dark. [Beilstein 8 IV 252.] |
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