IFLAB-BB F1950-0211 manufacturers
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| | IFLAB-BB F1950-0211 Basic information |
| Product Name: | IFLAB-BB F1950-0211 | | Synonyms: | IFLAB-BB F1950-0211;(5Z)-2-Amino-5-(3,4-dimethoxybenzylidene)-1,3-thiazol-4(5H)-one;(5Z)-5-(3,4-dimethoxybenzylidene)-2-imino-1,3-thiazolidin-4-one;WAY-119064;Inhibitor,Alzheimer’s disease,GSK-3,Glycogen synthase kinase-3,inhibit,Glycogen synthase kinase 3,WAY119064,GSK-3β inhibitor 10,WAY 119064;(Z)-2-Amino-5-(3,4-dimethoxybenzylidene)thiazol-4(5H)-one;4(5H)-Thiazolone, 2-amino-5-[(3,4-dimethoxyphenyl)methylene]-, (5Z)-;GSK-3β inhibitor 10 | | CAS: | 1198098-03-1 | | MF: | C12H12N2O3S | | MW: | 264.3 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | IFLAB-BB F1950-0211 Chemical Properties |
| Boiling point | 454.8±55.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 13 mg/mL (49.19 mM);Ethanol: Insoluble | | pka | -0.59±0.20(Predicted) | | form | Solid | | color | Light yellow to yellow | | Water Solubility | Water: Insoluble |
| | IFLAB-BB F1950-0211 Usage And Synthesis |
| Uses | GSK-3β inhibitor 10 (compound 14a) is a highly potent GSK-3β inhibitor with an IC50 value of 80.5 nM. GSK-3β inhibitor 10 can be used for researching Alzheimer’s disease[1]. | | Biological Activity | WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM. | | IC 50 | GSK-3β: 80.5 nM (IC50) | | References | [1] Arfeen M, et al. Eur J Med Chem. 2016 Oct 4;121:727-736. |
| | IFLAB-BB F1950-0211 Preparation Products And Raw materials |
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